ReviewBioengineering (Basel, Switzerland)2023
Bioceramics in Endodontics: Updates and Future Perspectives.
Review in Bioengineering (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
82 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Comparative efficacy of novel biomaterials versus traditional materials in the treatment of dental and pulpal diseases: a systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- Histological evaluation of vital full pulpotomy techniques in permanent mature teeth with symptomatic irreversible pulpitis using three calcium silicate cements: a randomized controlled trial.BMC oral health · 2025Trial
- Clinical and radiographic evaluation of premixed bioceramic putty as an apical plug in nonvital immature anterior permanent teeth.Scientific reports · 2025Trial
- Assessing the Success of a Mineral Trioxide Aggregate and a Pre-Mixed Bioceramic in Mature Teeth With Irreversible Pulpitis With Full Pulpotomy: A Randomized Clinical Trial.Clinical and experimental dental research · 2025Trial
- Regenerative endodontic treatment for premolars with apical root segment separation and extensive periapical lesions secondary to severe inflammatory root resorption: A report of two cases.Experimental and therapeutic medicine · 2026Article
- Pioneering next-generation bioactive materials for endodontics: Insights of mitochondrial biology.Bioactive materials · 2026Article
- Orthograde Apical Barrier in Non-Vital Immature Permanent Teeth: A Narrative Review of Clinical Pathways, Procedural Determinants, and Evidence Gaps.Dentistry journal · 2026Review
- Article
- Comparative Evaluation of Bio-C Temp and Calcium Hydroxide as Intracanal Medicaments in Managing Postoperative Pain and Percussion Sensitivity in Symptomatic Irreversible Pulpitis: A Preliminary Prospective Observational Cohort Study.Journal of clinical medicine · 2026Article
- Protein adsorption at material interface: mechanistic design framework for engineering ceramic scaffolds for bone repair applications.Biomedical engineering online · 2026Review
- Management of Ledge Formation and Perforations in Endodontics: A Survey of Knowledge, Attitudes, Practices, and Perceptions Among General Dental Practitioners and Endodontists.Journal of clinical and experimental dentistry · 2026Review
- Long-term outcome of combined orthograde and surgical management of perforating internal root resorption using a bioceramic repair material: an eight-year CBCT-documented case report.BMC oral health · 2026Article
- Dose-dependent effects of Metformin on proliferation and odontogenic differentiation of dental pulp stem cells.BMC oral health · 2026Article
- Bioactivity and dimensional stability of resin-, hybrid-, and silicate-based endodontic sealers: An in vitro comparative study.Journal of clinical and experimental dentistry · 2026Review
- Synergistic effects of collagen membrane and mineral trioxide aggregate on odontogenic differentiation and mineralization of human dental pulp stem cells: an in vitro study.BMC oral health · 2026Article
- Use of Bioceramic Sealers in Clinical Practice Among Dentists in Saudi Arabia: A Cross-Sectional Analysis.Cureus · 2026Article
- Oxidative Stress, Pro-Inflammatory Response, Cytotoxicity and Apoptosis Induced by Contemporary Endodontic Sealers in Human Periodontal Ligament Fibroblasts.Journal of functional biomaterials · 2026Article
- [Endodontic retreatment of a maxillary second molar with chronic apical periodontitis and separated instrument: A case report].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2026Article
- Nonsurgical retrieval of bioceramic materials using ultrasonics: a case report.Journal of medical case reports · 2026Article
- Fifty-year follow-up of dens invaginatus treated by nonsurgical and surgical endodontic treatments: a case report.Restorative dentistry & endodontics · 2026Article
22 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Bioceramics, with excellent bioactivity and biocompatibility, have been widely used in dentistry, particularly in endodontics. Mineral trioxide aggregate (MTA) is the most widely used bioceramic in endodontics. Recently, many new bioceramics have been developed, showing good potential for the treatment of endodontic diseases. This paper reviews the characteristics of bioceramics and their applications in various clinical endodontic situations, including root-end filling, root canal therapy, vital pulp therapy, apexification/regenerative endodontic treatment, perforation repair, and root defect repair. Relevant literature published from 1993 to 2023 was searched by keywords in PubMed and Web of Science. Current evidence supports the predictable outcome of MTA in the treatment of endodontic diseases. Although novel bioceramics such as Biodentine, EndoSequence, and calcium-enriched mixtures have shown promising clinical outcomes, more well-controlled clinical trials are still needed to provide high-level evidence for their application in endodontics. In addition, to better tackle the clinical challenges in endodontics, efforts are needed to improve the bioactivity of bioceramics, particularly to enhance their antimicrobial activity and mechanical properties and reduce their setting time and solubility.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.