Evidence map›Paper›PMID 36978895›Full record

ArticleAntioxidants (Basel, Switzerland)2023

Role of Cystathionine β-Synthase and 3-Mercaptopyruvate Sulfurtransferase in the Regulation of Proliferation, Migration, and Bioenergetics of Murine Breast Cancer Cells.

Sidneia Sousa Santos, Larissa de Oliveira Cavalcanti Peres Rodrigues, Vanessa Martins, Maria Petrosino, Karim Zuhra, Kelly Ascenção, Abhishek Anand, Reham Mahmoud Abdel-Kader, Mohamed Z Gad, Carole Bourquin and 1 more

Open access · goldFull text read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Sulfide regulation and catabolism in health and disease.Signal transduction and targeted therapy · 2025
    Review
  3. Review
  4. Emerging roles of hydrogen sulfide-metabolizing enzymes in cancer.Redox report : communications in free radical research · 2024
    Review
  5. Pan-inhibition of the three HCancer cell international · 2024
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Sidneia Sousa SantosDepartment of Medicine, Division of Infectious Diseases, Escola Paulista de Medicina, Federal University of São Paulo (EPM/UNIFESP), São Paulo 04023, Brazil.ORCID 0000-0002-6807-9881
Larissa de Oliveira Cavalcanti Peres RodriguesDepartment of Medicine, Division of Infectious Diseases, Escola Paulista de Medicina, Federal University of São Paulo (EPM/UNIFESP), São Paulo 04023, Brazil.ORCID 0000-0001-6935-290X
Vanessa MartinsChair of Pharmacology, Section of Science and Medicine, University of Fribourg, 1700 Fribourg, Switzerland.
Maria PetrosinoChair of Pharmacology, Section of Science and Medicine, University of Fribourg, 1700 Fribourg, Switzerland.ORCID 0000-0001-7875-5954
Karim ZuhraChair of Pharmacology, Section of Science and Medicine, University of Fribourg, 1700 Fribourg, Switzerland.ORCID 0000-0003-0186-1817
Kelly AscençãoChair of Pharmacology, Section of Science and Medicine, University of Fribourg, 1700 Fribourg, Switzerland.ORCID 0000-0001-6693-6897
Abhishek AnandChair of Pharmacology, Section of Science and Medicine, University of Fribourg, 1700 Fribourg, Switzerland.ORCID 0000-0001-8055-6970
Reham Mahmoud Abdel-KaderPharmacology and Toxicology Department, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo 11511, Egypt.ORCID 0000-0003-3584-0045
Mohamed Z GadDepartment of Biochemistry, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo 11511, Egypt.ORCID 0000-0003-1173-8628
Carole BourquinSchool of Pharmaceutical Sciences, Institute of Pharmaceutical Sciences of Western Switzerland, Department of Anaesthesiology, Pharmacology, Intensive Care and Emergency Medicine, University of Geneva, 1211 Geneva, Switzerland.ORCID 0000-0003-3862-4583
Csaba SzaboChair of Pharmacology, Section of Science and Medicine, University of Fribourg, 1700 Fribourg, Switzerland.ORCID 0000-0003-3110-4235
University of Fribourg · CHGerman University in Cairo · EGUniversity of Geneva · CH

Funding

Swiss National Science Foundation SNF IZSTZ0_198887
6 · The paper itself

Abstract

Cystathionine β-synthase (CBS), CSE (cystathionine γ-lyase) and 3-mercaptopyruvate sulfurtransferase (3-MST) have emerged as three significant sources of hydrogen sulfide (H

Indexed as

bioenergeticsgasotransmittershydrogen sulfidemigrationmitochondrianitric oxideproliferation

Identifiers

PMID36978895
PMCPMC10045476
OpenAlexW4323313074

What Socratic holds

Textfull text, public
LicenceCC BY
measurements read39
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.