Evidence map›Paper›PMID 36979014›Full record

ArticleAntioxidants (Basel, Switzerland)2023

Photobiomodulation Controls Keratinocytes Inflammatory Response through Nrf2 and Reduces Langerhans Cells Activation.

Sara Salman, Cyprien Guermonprez, Laurent Peno-Mazzarino, Elian Lati, Audrey Rousseaud, Lieve Declercq, Saadia Kerdine-Römer

Open access · goldFull text read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 30 citations in OpenAlex.

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  14. Bmi-1 plays an important role in preventing bone aging by regulating the bone microenvironment.International journal of clinical and experimental pathology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Sara SalmanInserm, Inflammation Microbiome Immunosurveillance, Université Paris-Saclay, 91400 Orsay, France.
Cyprien GuermonprezLightinderm, Pépinière Paris Santé Cochin, Hôpital Cochin, 75014 Paris, France.
Laurent Peno-MazzarinoLaboratoire BIO-EC, 91160 Longjumeau, France.ORCID 0000-0003-1753-9355
Elian LatiLaboratoire BIO-EC, 91160 Longjumeau, France.
Audrey RousseaudLightinderm, Pépinière Paris Santé Cochin, Hôpital Cochin, 75014 Paris, France.
Lieve DeclercqLightinderm, Pépinière Paris Santé Cochin, Hôpital Cochin, 75014 Paris, France.
Saadia Kerdine-RömerInserm, Inflammation Microbiome Immunosurveillance, Université Paris-Saclay, 91400 Orsay, France.ORCID 0000-0003-3313-952X
Hôpital Cochin · FRInserm · FR

Funding

Lightinderm ANRT
6 · The paper itself

Abstract

Photobiomodulation (PBM) is rapidly gaining traction as a valuable tool in dermatology for treating many inflammatory skin conditions using low levels of visible light or near-infrared radiation. However, the physiological regulatory pathways responsible for the anti-inflammatory effect of PBM have not been well defined. Since previous studies showed that nuclear factor-erythroid 2 like 2 (Nrf2) is a master regulator of the skin inflammatory response, we have addressed its role in controlling inflammation by PBM. Primary human keratinocytes (KCs) stimulated with 2,4-dinitrochlorobenzene (DNCB) to mimic pro-inflammatory stress were illuminated with two wavelengths: 660 nm or 520 nm. Both lights significantly reduced the mRNA expression of the DNCB-triggered

Indexed as

immunomodulationinflammationkeratinocyteLangerhans cellslightNrf2photobiomodulationskin

Identifiers

PMID36979014
PMCPMC10045240
OpenAlexW4328098737

What Socratic holds

Textfull text, public
LicenceCC BY
measurements read74
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.