Evidence mapPaperPMID 36979141Full record

ReviewBiology2023

Microalgae as a Nutraceutical Tool to Antagonize the Impairment of Redox Status Induced by SNPs: Implications on Insulin Resistance.

Mattia Melloni, Domenico Sergi, Carolina Simioni, Angelina Passaro, Luca Maria Neri

Open access · goldFull text readReview
In one paragraph

Review in Biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Mattia MelloniDepartment of Translational Medicine, University of Ferrara, Via Luigi Borsari 46, 44121 Ferrara, Italy.ORCID 0000-0003-3987-7267
Domenico SergiDepartment of Translational Medicine, University of Ferrara, Via Luigi Borsari 46, 44121 Ferrara, Italy.ORCID 0000-0002-3001-410X
Carolina SimioniDepartment of Life Sciences and Biotechnology, University of Ferrara, Via Fossato di Mortara 70, 44121 Ferrara, Italy.
Angelina PassaroDepartment of Translational Medicine, University of Ferrara, Via Luigi Borsari 46, 44121 Ferrara, Italy.ORCID 0000-0001-8462-7000
Luca Maria NeriDepartment of Translational Medicine, University of Ferrara, Via Luigi Borsari 46, 44121 Ferrara, Italy.ORCID 0000-0002-7924-1477
University of Ferrara · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microalgae represent a growing innovative source of nutraceuticals such as carotenoids and phenolic compound which are naturally present within these single-celled organisms or can be induced in response to specific growth conditions. The presence of the unfavourable allelic variant in genes involved in the control of oxidative stress, due to one or more SNPs in gene encoding protein involved in the regulation of redox balance, can lead to pathological conditions such as insulin resistance, which, in turn, is directly involved in the pathogenesis of type 2 diabetes mellitus. In this review we provide an overview of the main SNPs in antioxidant genes involved in the promotion of insulin resistance with a focus on the potential role of microalgae-derived antioxidant molecules as novel nutritional tools to mitigate oxidative stress and improve insulin sensitivity.

Indexed as

antioxidantsinsulin resistancemicroalgaenutraceuticalsoxidative stressreactive oxygen speciessingle nucleotide polymorphisms

Identifiers

PMID36979141
PMCPMC10044993
OpenAlexW4324358634

What Socratic holds

Textfull text, public
LicenceCC BY
measurements read16
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.