Evidence map›Paper›PMID 36979406›Full record

ReviewBiomolecules2023

The Lysophospholipase PNPLA7 Controls Hepatic Choline and Methionine Metabolism.

Sayaka Harada, Yoshitaka Taketomi, Toshiki Aiba, Mai Kawaguchi, Tetsuya Hirabayashi, Baasanjav Uranbileg, Makoto Kurano, Yutaka Yatomi, Makoto Murakami

Open access · goldFull text readReview
In one paragraph

Review in Biomolecules, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. TreC: A Critical Mediator of lysoPC-Induced Hypervirulence inTransboundary and emerging diseases · 2026
    Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Sayaka HaradaLaboratory of Microenvironmental and Metabolic Health Sciences, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.
Yoshitaka TaketomiLaboratory of Microenvironmental and Metabolic Health Sciences, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.ORCID 0000-0003-4094-9846
Toshiki AibaDepartment of Radiation Effects Research, National Institutes for Quantum and Radiological Science and Technology, Chiba 263-8555, Japan.
Mai KawaguchiLaboratory of Microenvironmental and Metabolic Health Sciences, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.
Tetsuya HirabayashiLaboratory of Biomembrane, Department of Basic Medical Sciences, Tokyo Metropolitan Institute of Medical Science, Tokyo 156-8506, Japan.ORCID 0000-0001-8099-5367
Baasanjav UranbilegDepartment of Clinical Laboratory Medicine, The University of Tokyo, Tokyo 113-8655, Japan.
Makoto KuranoDepartment of Clinical Laboratory Medicine, The University of Tokyo, Tokyo 113-8655, Japan.
Yutaka YatomiDepartment of Clinical Laboratory Medicine, The University of Tokyo, Tokyo 113-8655, Japan.ORCID 0000-0003-1719-4297
Makoto MurakamiLaboratory of Microenvironmental and Metabolic Health Sciences, Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan.ORCID 0000-0002-4565-6017
The University of Tokyo · JPTokyo Metropolitan Institute of Medical Science · JPNational Institutes for Quantum Science and Technology · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The in vivo roles of lysophospholipase, which cleaves a fatty acyl ester of lysophospholipid, remained unclear. Recently, we have unraveled a previously unrecognized physiological role of the lysophospholipase PNPLA7, a member of the Ca

Indexed as

CholineLysophospholipaseAnimalsCarboxylic Ester HydrolasesGlycerylphosphorylcholineHumansLiverMethionineMiceS-AdenosylmethionineCarboxylic Ester HydrolasesCholineGlycerylphosphorylcholineLysophospholipaseMethioninePNPLA7 protein, humanPnpla7 protein, mouseS-Adenosylmethioninecholineglycerophosphocholineliverlysophosphatidylcholinelysophospholipasemethioninemethyl groupphosphatidylcholinephospholipase A2S-adenosylmethionine

Identifiers

PMID36979406
PMCPMC10046082
OpenAlexW4323318891

What Socratic holds

Textfull text, public
LicenceCC BY
measurements read13
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.