Evidence map›Paper›PMID 36979594›Full record

ArticleBiosensors2023

Simultaneous Measurement of Changes in Mitochondrial and Endoplasmic Reticulum Free Calcium in Pancreatic Beta Cells.

Sivakumar Jeyarajan, Irina X Zhang, Peter Arvan, Stephen I Lentz, Leslie S Satin

Open access · goldFull text read
In one paragraph

Article in Biosensors, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Role of Mitochondrial Dysfunction in Neuropathy.International journal of molecular sciences · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sivakumar JeyarajanDepartment of Pharmacology, University of Michigan Medical School, Ann Arbor, MI 48105, USA.ORCID 0000-0001-6614-5489
Irina X ZhangDepartment of Pharmacology, University of Michigan Medical School, Ann Arbor, MI 48105, USA.ORCID 0000-0003-0078-1225
Peter ArvanDepartment of Internal Medicine, Division of Metabolism, Endocrinology & Diabetes, University of Michigan Medical School, Ann Arbor, MI 48105, USA.ORCID 0000-0002-4007-8799
Stephen I LentzDepartment of Internal Medicine, Division of Metabolism, Endocrinology & Diabetes, University of Michigan Medical School, Ann Arbor, MI 48105, USA.
Leslie S SatinDepartment of Pharmacology, University of Michigan Medical School, Ann Arbor, MI 48105, USA.
University of Michigan · US

Funding

Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DAVID P OLSON · 2013 to 2026
$24.3M
Proinsulin Trafficking for Insulin BiosynthesisR01DK048280 · NIDDK · YESHIVA UNIVERSITY · PI ARVAN, PETER · 1994 to 2024
$10.5M
METABOLICALLY-COUPLED ION CHANNEL INTERACTIONS IN ISLETSR01DK046409 · NIDDK · VIRGINIA COMMONWEALTH UNIVERSITY · PI SATIN, LESLIE S. · 1994 to 2023
$9.1M
A Stress-Induced Vicious Cycle In The Development of T1DU01DK127747 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ARVAN, PETER, SATIN, LESLIE S. · 2020 to 2023
$2.8M
NIDDK NIH HHS P30 DK020572NIDDK NIH HHS R01 DK046409NIDDK NIH HHS R01 DK048280NIDDK NIH HHS RO1 DK46409NIDDK NIH HHS U01 DK127747NIDDK NIH HHS U01 DK127747-01
6 · The paper itself

Abstract

The free calcium (Ca

Indexed as

Insulin-Secreting CellsCalciumEndoplasmic ReticulumInsulin SecretionMitochondriaCalciumgenetically encoded calcium sensorsinsulinlive cell imagingmetabolismoscillations

Identifiers

PMID36979594
PMCPMC10046164
OpenAlexW4324141196

What Socratic holds

Textfull text, public
LicenceCC BY
measurements read11
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.