Evidence mapPaperPMID 36979631Full record

ArticleBiomedicines2023

Newborns from Mothers Who Intensely Consumed Sucralose during Pregnancy Are Heavier and Exhibit Markers of Metabolic Alteration and Low-Grade Systemic Inflammation: A Cross-Sectional, Prospective Study.

José Alfredo Aguayo-Guerrero, Lucía Angélica Méndez-García, Aarón Noe Manjarrez-Reyna, Marcela Esquivel-Velázquez, Sonia León-Cabrera, Guillermo Meléndez, Elena Zambrano, Espiridión Ramos-Martínez, José Manuel Fragoso, Juan Carlos Briones-Garduño and 1 more

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In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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  8. Biological and Behavioral Responses ofInternational journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

José Alfredo Aguayo-GuerreroLaboratory of Immunometabolism, Research Division, General Hospital of Mexico "Dr. Eduardo Liceaga", Mexico City 06720, Mexico.
Lucía Angélica Méndez-GarcíaLaboratory of Immunometabolism, Research Division, General Hospital of Mexico "Dr. Eduardo Liceaga", Mexico City 06720, Mexico.ORCID 0000-0001-7576-5209
Aarón Noe Manjarrez-ReynaLaboratory of Immunometabolism, Research Division, General Hospital of Mexico "Dr. Eduardo Liceaga", Mexico City 06720, Mexico.ORCID 0000-0002-5194-228X
Marcela Esquivel-VelázquezLaboratory of Proteomics, Research Division, General Hospital of Mexico "Dr. Eduardo Liceaga", Mexico City 06720, Mexico.ORCID 0000-0002-2975-8603
Sonia León-CabreraUnidad de Biomedicina, Facultad de Estudios Superiores-Iztacala, Universidad Nacional Autónoma de México, Tlalnepantla 54090, Mexico.ORCID 0000-0002-1661-5013
Guillermo MeléndezResearch Department, Universidad Autónoma de Nuevo León, Monterrey 64460, Mexico.
Elena ZambranoReproductive Biology Department, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City 14080, Mexico.ORCID 0000-0002-0362-9117
Espiridión Ramos-MartínezExperimental Medicine Research Unit, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City 06720, Mexico.ORCID 0000-0002-4361-821X
José Manuel FragosoDepartment of Molecular Biology, Instituto Nacional de Cardiología "Ignacio Chávez", Juan Badiano 1, Sección XVI, Tlalpan, Mexico City 14080, Mexico.ORCID 0000-0003-3137-7815
Juan Carlos Briones-GarduñoDepartment of Gynecology, General Hospital of Mexico "Dr. Eduardo Liceaga", Mexico City 06720, Mexico.
Galileo EscobedoLaboratory of Immunometabolism, Research Division, General Hospital of Mexico "Dr. Eduardo Liceaga", Mexico City 06720, Mexico.ORCID 0000-0002-9224-7400

Funding

Consejo Nacional de Ciencia y Tecnología SALUD-2017-02-290345
6 · The paper itself

Abstract

Robust data in animals show that sucralose intake during gestation can predispose the offspring to weight gain, metabolic disturbances, and low-grade systemic inflammation; however, concluding information remains elusive in humans. In this cross-sectional, prospective study, we examined the birth weight, glucose and insulin cord blood levels, monocyte subsets, and inflammatory cytokine profile in 292 neonates at term from mothers with light sucralose ingestion (LSI) of less than 60 mg sucralose/week or heavy sucralose intake (HSI) of more than 36 mg sucralose/day during pregnancy. Mothers in the LSI (

Indexed as

birth weightcord bloodIL-10insulinmonocyte subsetneonatepregnancysucraloseTNF-alpha

Identifiers

PMID36979631
PMCPMC10045555

What Socratic holds

Textfull text, public
LicenceCC BY
measurements read23
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.