Evidence map›Paper›PMID 36979693›Full record

ArticleBiomedicines2023

Cardioprotective Effects of a Selective c-Jun N-terminal Kinase Inhibitor in a Rat Model of Myocardial Infarction.

Mark B Plotnikov, Galina A Chernysheva, Vera I Smol'yakova, Oleg I Aliev, Tatyana I Fomina, Lyubov A Sandrikina, Irina V Sukhodolo, Vera V Ivanova, Anton N Osipenko, Nina D Anfinogenova and 4 more

Open access · goldFull text read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

  1. Chemistry and Biological Activity of 11Molecules (Basel, Switzerland) · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. The role of mechanosignaling in the control of myocardial mass.American journal of physiology. Heart and circulatory physiology · 2025
    Review
  6. Article
  7. Mitochondrial Kinase Signaling for Cardioprotection.International journal of molecular sciences · 2024
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Mark B PlotnikovDepartment of Pharmacology, Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences, 634028 Tomsk, Russia.ORCID 0000-0002-0548-6586
Galina A ChernyshevaDepartment of Pharmacology, Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences, 634028 Tomsk, Russia.
Vera I Smol'yakovaDepartment of Pharmacology, Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences, 634028 Tomsk, Russia.
Oleg I AlievDepartment of Pharmacology, Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences, 634028 Tomsk, Russia.
Tatyana I FominaDepartment of Pharmacology, Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences, 634028 Tomsk, Russia.
Lyubov A SandrikinaDepartment of Pharmacology, Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences, 634028 Tomsk, Russia.
Irina V SukhodoloDepartment of Morphology and General Pathology, Siberian State Medical University, 634050 Tomsk, Russia.
Vera V IvanovaDepartment of Morphology and General Pathology, Siberian State Medical University, 634050 Tomsk, Russia.ORCID 0000-0002-2530-1112
Anton N OsipenkoDepartment of Pharmacology, Siberian State Medical University, 634050 Tomsk, Russia.ORCID 0000-0002-4763-3214
Nina D AnfinogenovaCardiology Research Institute, Tomsk National Research Medical Center, Russian Academy of Sciences, 634012 Tomsk, Russia.ORCID 0000-0003-1106-0730
Andrei I KhlebnikovKizhner Research Center, Tomsk Polytechnic University, 634050 Tomsk, Russia.ORCID 0000-0002-3022-4510
Dmitriy N AtochinKizhner Research Center, Tomsk Polytechnic University, 634050 Tomsk, Russia.
Igor A SchepetkinDepartment of Microbiology and Cell Biology, Montana State University, Bozeman, MT 59717, USA.
Mark T QuinnDepartment of Microbiology and Cell Biology, Montana State University, Bozeman, MT 59717, USA.ORCID 0000-0001-8114-5073
Russian Academy of Sciences · RUSiberian State Medical University · RUMontana State University · USHarvard University · USNational Research Tomsk State University · RU

Funding

Research Core (Developmental Research Project Program)P20GM103474 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI Ann Therese Bertagnolli · 2012 to 2026
$60.0M
NIGMS NIH HHS P20 GM103474NIH HHS GM103474
6 · The paper itself

Abstract

Activation of c-Jun N-terminal kinases (JNKs) is involved in myocardial injury, left ventricular remodeling (LV), and heart failure (HF) after myocardial infarction (MI). The aim of this research was to evaluate the effects of a selective JNK inhibitor, 11

Indexed as

11H-indeno[1,2-b]quinoxalin-11-one oximecardioprotective activityc-Jun N-terminal kinase inhibitorheart failureinfarct sizeischemia/reperfusionmyocardial infarction

Identifiers

PMID36979693
PMCPMC10044897
OpenAlexW4322500213

What Socratic holds

Textfull text, public
LicenceCC BY
measurements read55
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.