Evidence map›Paper›PMID 36979790›Full record

ArticleBiomedicines2023

Synthesis, In Vitro Biological Evaluation of Antiproliferative and Neuroprotective Effects and In Silico Studies of Novel 16

Vanessa Brito, Mariana Marques, Marta Esteves, Catarina Serra-Almeida, Gilberto Alves, Paulo Almeida, Liliana Bernardino, Samuel Silvestre

Open access · goldFull text read
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Vanessa BritoCICS-UBI-Health Sciences Research Centre, University of Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal.ORCID 0000-0002-8030-9379
Mariana MarquesCICS-UBI-Health Sciences Research Centre, University of Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal.
Marta EstevesCICS-UBI-Health Sciences Research Centre, University of Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal.
Catarina Serra-AlmeidaCICS-UBI-Health Sciences Research Centre, University of Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal.ORCID 0000-0002-8606-7630
Gilberto AlvesCICS-UBI-Health Sciences Research Centre, University of Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal.ORCID 0000-0002-4213-0714
Paulo AlmeidaCICS-UBI-Health Sciences Research Centre, University of Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal.ORCID 0000-0003-0110-4795
Liliana BernardinoCICS-UBI-Health Sciences Research Centre, University of Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal.
Samuel SilvestreCICS-UBI-Health Sciences Research Centre, University of Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal.ORCID 0000-0003-4297-5108
University of Beira Interior · PT

Funding

BID/ICI-FC/Santander Universidades-UBI/2016 BID/ICI-FC/Santander Universidades-UBI/2016 (VB)C4-Cloud Computing Competences Center CENTRO-01-0145-FEDER-000019FCT - Foundation for Science and Technology Project UID/ Multi/00709FCT - Foundation for Science and Technology SFRH/BD/131059/ 2017POCI - COMPETE 2020 - Operational Programme Competitiveness and Internationalization in Axis I - Strengthening Research, Technological Development and Innovation Project No. 007491Portuguese NMR Network (PTNMR) Infrastructure Project No. 022161
6 · The paper itself

Abstract

Steroids constitute an important class of pharmacologically active molecules, playing key roles in human physiology. Within this group, 16

Indexed as

16E-arylidene-5α,6α-epoxyepiandrosterone derivativesaldol condensationantiproliferative activityapoptosisepoxidationmolecular docking

Identifiers

PMID36979790
PMCPMC10045663
OpenAlexW4323565114

What Socratic holds

Textfull text, public
LicenceCC BY
measurements read116
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.