Evidence map›Paper›PMID 36979931›Full record

ReviewBiomedicines2023

Clinical Relevance of Gut Microbiota Alterations under the Influence of Selected Drugs-Updated Review.

Honorata Mruk-Mazurkiewicz, Monika Kulaszyńska, Karolina Jakubczyk, Katarzyna Janda-Milczarek, Wiktoria Czarnecka, Ewa Rębacz-Maron, Sławomir Zacha, Jerzy Sieńko, Samir Zeair, Bartosz Dalewski and 3 more

Open access · goldFull text readReview
In one paragraph

Review in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Gut microbiota's role in heart failure.Heart failure reviews · 2025
    Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Honorata Mruk-MazurkiewiczDepartment of Biochemical Science, Pomeranian Medical University in Szczecin, 71-460 Szczecin, Poland.
Monika KulaszyńskaDepartment of Biochemical Science, Pomeranian Medical University in Szczecin, 71-460 Szczecin, Poland.
Karolina JakubczykDepartment of Human Nutrition and Metabolomics, Pomeranian Medical University in Szczecin, 71-460 Szczecin, Poland.ORCID 0000-0002-5853-9709
Katarzyna Janda-MilczarekDepartment of Human Nutrition and Metabolomics, Pomeranian Medical University in Szczecin, 71-460 Szczecin, Poland.ORCID 0000-0002-4548-3419
Wiktoria CzarneckaDepartment of Biochemical Science, Pomeranian Medical University in Szczecin, 71-460 Szczecin, Poland.
Ewa Rębacz-MaronInstitute of Biology, Department of Ecology and Anthropology, University of Szczecin, 71-415 Szczecin, Poland.ORCID 0000-0002-3675-2541
Sławomir ZachaDepartment of Pediatric Orthopedics and Oncology of the Musculoskeletal System, Pomeranian Medical University in Szczecin, 71-252 Szczecin, Poland.
Jerzy SieńkoDepartment of General and Gastroenterology Oncology Surgery, Pomeranian Medical University in Szczecin, 71-899 Szczecin, Poland.
Samir ZeairGeneral and Transplant Surgery Ward with Sub-Departments of Pomeranian Regional Hospital in Szczecin, 71-455 Arkonska, Poland.
Bartosz DalewskiDepartment of Dental Prosthetics, Pomeranian Medical University in Szczecin, 70-111 Szczecin, Poland.ORCID 0000-0002-0652-664X
Wojciech MarliczDepartment of Gastroenterology, Pomeranian Medical University in Szczecin, 71-455 Szczecin, Poland.ORCID 0000-0002-2649-5967
Igor ŁoniewskiDepartment of Biochemical Science, Pomeranian Medical University in Szczecin, 71-460 Szczecin, Poland.
Karolina Skonieczna-ŻydeckaDepartment of Biochemical Science, Pomeranian Medical University in Szczecin, 71-460 Szczecin, Poland.ORCID 0000-0002-3430-9079
Pomeranian Medical University · PLUniversity of Szczecin · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As pharmacology and science progress, we discover new generations of medicines. This relationship is a response to the increasing demand for medicaments and is powered by progress in medicine and research about the respective entities. However, we have questions about the efficiency of pharmacotherapy in individual groups of patients. The effectiveness of therapy is controlled by many variables, such as genetic predisposition, age, sex and diet. Therefore, we must also pay attention to the microbiota, which fulfill a lot of functions in the human body. Drugs used in psychiatry, gastroenterology, diabetology and other fields of medicine have been demonstrated to possess much potential to change the composition and probably the function of the intestinal microbiota, which consequently creates long-term risks of developing chronic diseases. The article describes the amazing interactions between gut microbes and drugs currently used in healthcare.

Indexed as

drugsinteractionsmicrobiotapharmacotherapyphytochemicals

Identifiers

PMID36979931
PMCPMC10046554
OpenAlexW4327949780

What Socratic holds

Textfull text, public
LicenceCC BY
measurements read4
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.