Evidence map›Paper›PMID 36981477›Full record

ReviewHealthcare (Basel, Switzerland)2023

Effects of Exercise and Physical Activity Levels on Childhood Cancer: An Umbrella Review.

Christina Rapti, Petros C Dinas, Costas Chryssanthopoulos, Alexandra Mila, Anastassios Philippou

Registry-linked trialOpen access · goldFull text readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Healthcare (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06813950 (IMPACT of a PHYSICAL ACTIVITY PROGRAM on the HEALTH-RELATED QUALITY of LIFE in PEDIATRIC CANCER PATIENTS), which is not on this map. Cited by 26 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 3 pooled it
16.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06813950 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

IMPACT of a PHYSICAL ACTIVITY PROGRAM on the HEALTH-RELATED QUALITY of LIFE in PEDIATRIC CANCER PATIENTS

TypeinterventionalSponsorSociedad de Lucha Contra el CáncerRan2025 to 2025Enrolled80ConditionsCancer, Pediatric CancerArmsPhysical activity
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Christina RaptiDepartment of Physiology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Petros C DinasFAME Laboratory, Department of Physical Education and Sport Science, University of Thessaly, 42100 Trikala, Greece.ORCID 0000-0001-6853-9238
Costas ChryssanthopoulosDepartment of Physiology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Alexandra MilaDepartment of Physiology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Anastassios PhilippouDepartment of Physiology, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0000-0003-0047-3003
National and Kapodistrian University of Athens · GRUniversity of Thessaly · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients and survivors of childhood cancer experience adverse effects related to the disease and its treatment. These adverse effects are associated with both physiological and psychological health. Exercise helps manage the side effects and improve the health outcomes. The objective of this umbrella review is to search the current literature in the context of exercise and physical activity as complementary interventions on pediatric cancer and to provide comprehensive information about the derived health outcomes. A literature search was conducted on the Cochrane, PubMed, and Embase databases for systematic reviews published up to January 2023. Moreover, a hand search of reference lists was performed. We included participants under 19 years of age at diagnosis of any type of childhood cancer, without restriction on the type or phase of treatment, who participated in exercise interventions. The results showed a beneficial impact on fatigue, muscle strength, aerobic capacity, activity and participation levels, psychosocial health, cardiovascular/cardiorespiratory fitness, physical function, bone mineral density, and brain volume and structure, with limited and not serious adverse effects. These findings documented that exercise interventions had a positive effect on many physiological and psychological health outcomes in pediatric cancer patients and survivors.

Indexed as

adolescentschildrenmalignancyphysical trainingsystematic review

Identifiers

PMID36981477
PMCPMC10048410
OpenAlexW4324056246

What Socratic holds

Textfull text, public
LicenceCC BY
measurements read37
identifiers read1
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.