Evidence map›Paper›PMID 36982429›Full record

ArticleInternational journal of molecular sciences2023

Combinatorial Network of Transcriptional and miRNA Regulation in Colorectal Cancer.

Rupesh Kumar, Maged Mostafa Mahmoud, Hanaa M Tashkandi, Shafiul Haque, Steve Harakeh, Kalaiarasan Ponnusamy, Shazia Haider

Open access · goldFull text read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 5 countries.

Rupesh KumarDepartment of Biotechnology, Jaypee Institute of Information Technology, A-10, Sector 62, Noida 201309, India.
Maged Mostafa MahmoudKing Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Hanaa M TashkandiDepartment of General Surgery, Faculty of Medicine, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Shafiul HaqueResearch and Scientific Studies Unit, College of Nursing and Allied Health Sciences, Jazan University, Jazan 45142, Saudi Arabia.ORCID 0000-0002-2989-121X
Steve HarakehKing Fahd Medical Research Center, and Yousef Abdullatif Jameel Chair of Prophetic Medicine Application, Faculty of Medicine, King Abdulaziz University, Jeddah 21589, Saudi Arabia.ORCID 0000-0001-7512-8787
Kalaiarasan PonnusamyBiotechnology Division, National Centre for Disease Control, New Delhi 110054, India.
Shazia HaiderDepartment of Biotechnology, Jaypee Institute of Information Technology, A-10, Sector 62, Noida 201309, India.
King Abdulaziz University · SAJaypee Institute of Information Technology · INAjman University · AENational Center for Disease Control · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer is one of the leading causes of cancer-associated mortality across the worldwide. One of the major challenges in colorectal cancer is the understanding of the regulatory mechanisms of biological molecules. In this study, we aimed to identify novel key molecules in colorectal cancer by using a computational systems biology approach. We constructed the colorectal protein-protein interaction network which followed hierarchical scale-free nature. We identified

Indexed as

Colorectal NeoplasmsMicroRNAsComputational BiologyErbB ReceptorsGene Expression RegulationGene Expression Regulation, NeoplasticGene Regulatory NetworksHumansTranscription FactorsErbB ReceptorsMicroRNAsMIRN622 microRNA, humanTranscription Factorsbottleneck-hubscolorectal cancermiRNAsprotein–protein interactionregulatorssub-networktranscription factors

Identifiers

PMID36982429
PMCPMC10048903
OpenAlexW4324061304

What Socratic holds

Textfull text, public
LicenceCC BY
reference markers read1
measurements read16
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.