Evidence map›Paper›PMID 36982905›Full record

ArticleInternational journal of molecular sciences2023

Drug Repositioning as a Therapeutic Strategy against

Laura Ortiz-Miravalles, Manuel Sánchez-Angulo, Jesús M Sanz, Beatriz Maestro

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

  1. Artificial Intelligence-Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
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  7. Serotype-Dependent Inhibition ofJournal of microbiology and biotechnology · 2024
    Article
  8. International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Laura Ortiz-MiravallesProtein Engineering against Antimicrobial Resistance Group, Centro de Investigaciones Biológicas Margarita Salas, Consejo Superior de Investigaciones Científicas (CSIC), 28040 Madrid, Spain.
Manuel Sánchez-AnguloDepartment of Vegetal Production and Microbiology, Universidad Miguel Hernández, 03202 Elche, Spain.ORCID 0000-0002-4200-3117
Jesús M SanzProtein Engineering against Antimicrobial Resistance Group, Centro de Investigaciones Biológicas Margarita Salas, Consejo Superior de Investigaciones Científicas (CSIC), 28040 Madrid, Spain.ORCID 0000-0002-4421-9376
Beatriz MaestroProtein Engineering against Antimicrobial Resistance Group, Centro de Investigaciones Biológicas Margarita Salas, Consejo Superior de Investigaciones Científicas (CSIC), 28040 Madrid, Spain.
Universidad Complutense de Madrid · ESConsejo Superior de Investigaciones Científicas · ESUniversitat de Miguel Hernández d'Elx · ES

Funding

Agencia Estatal de Investigación (Spain) PID2019-105126RB-I00Centro de Investigación Biomédica en Red CIBERESNDT2325
6 · The paper itself

Abstract

A collection of repurposing drugs (Prestwick Chemical Library) containing 1200 compounds was screened to investigate the drugs' antimicrobial effects against planktonic cultures of the respiratory pathogen

Indexed as

Anti-Infective AgentsPneumococcal InfectionsAnti-Bacterial AgentsCell MembraneDrug RepositioningHumansMicrobial Sensitivity TestsMitoxantroneStreptococcus pneumoniaeAnti-Bacterial AgentsAnti-Infective AgentsMitoxantroneantimicrobial resistancedrug repurposingmembrane permeabilitypneumococcus

Identifiers

PMID36982905
PMCPMC10058218
OpenAlexW4327963741

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.