Evidence mapPaperPMID 36983294Full record

ReviewJournal of clinical medicine2023

Hidden Comorbidities in Asthma: A Perspective for a Personalized Approach.

Matteo Maule, Bianca Olivieri, Gabriella Guarnieri, Lucia De Franceschi, Nicola Martinelli, Rachele Vaia, Giuseppe Argentino, Andrea Vianello, Gianenrico Senna, Marco Caminati

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Pediatric asthma comorbidities: Global impact and unmet needs.The World Allergy Organization journal · 2024
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Matteo MauleAllergy Unit and Asthma Center, Verona University Hospital, 37134 Verona, Italy.
Bianca OlivieriAllergy Unit and Asthma Center, Verona University Hospital, 37134 Verona, Italy.ORCID 0000-0003-1690-6774
Gabriella GuarnieriDepartment of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, 35128 Padua, Italy.
Lucia De FranceschiDepartment of Medicine, University of Verona, 35134 Verona, Italy.ORCID 0000-0001-7093-777X
Nicola MartinelliDepartment of Medicine, University of Verona, 35134 Verona, Italy.ORCID 0000-0001-6465-5119
Rachele VaiaAllergy Unit and Asthma Center, Verona University Hospital, 37134 Verona, Italy.
Giuseppe ArgentinoDepartment of Medicine, University of Verona, 35134 Verona, Italy.ORCID 0000-0002-4747-4655
Andrea VianelloDepartment of Cardiac Thoracic Vascular Sciences and Public Health, University of Padova, 35128 Padua, Italy.
Gianenrico SennaAllergy Unit and Asthma Center, Verona University Hospital, 37134 Verona, Italy.ORCID 0000-0003-4172-3216
Marco CaminatiDepartment of Medicine, University of Verona, 35134 Verona, Italy.ORCID 0000-0001-7383-1487
University of Verona · ITUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bronchial asthma is the most frequent inflammatory non-communicable condition affecting the airways worldwide. It is commonly associated with concomitant conditions, which substantially contribute to its burden, whether they involve the lung or other districts. The present review aims at providing an overview of the recent acquisitions in terms of asthma concomitant systemic conditions, besides the commonly known respiratory comorbidities. The most recent research has highlighted a number of pathobiological interactions between asthma and other organs in the view of a shared immunological background underling different diseases. A bi-univocal relationship between asthma and common conditions, including cardiovascular, metabolic or neurodegenerative diseases, as well as rare disorders such as sickle cell disease, α1-Antitrypsin deficiency and immunologic conditions with hyper-eosinophilia, should be considered and explored, in terms of diagnostic work-up and long-term assessment of asthma patients. The relevance of that acquisition is of utmost importance in the management of asthma patients and paves the way to a new approach in the light of a personalized medicine perspective, besides targeted therapies.

Indexed as

asthmacardiovascular riskcognitive impairmenteosinophilsimmunodeficienciesobesitysickle cell diseasewheezingα1-Antitrypsin deficiency

Identifiers

PMID36983294
PMCPMC10059265
OpenAlexW4327621852

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.