Evidence map›Paper›PMID 36985183›Full record

ReviewMicroorganisms2023

The Role of Biofilms in the Pathogenesis of Animal Bacterial Infections.

Live L Nesse, Ane Mohr Osland, Lene K Vestby

Open access · goldAbstract readReview
In one paragraph

Review in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Comparative Biofilmomics of Antimicrobial-ResistantAnimals : an open access journal from MDPI · 2026
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Characterization of biofilm and exopolysaccharide production in Bacillus strains isolated from the bovine uterus.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Serovar-specific genomic features ofFrontiers in molecular biosciences · 2025
    Article
  15. Article
  16. Antimicrobial and Antibiofilm Potential ofPlants (Basel, Switzerland) · 2024
    Article
  17. Review
  18. Review
  19. Review
  20. TheMicroorganisms · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Live L NesseDepartment of Animal Health, Welfare and Food Safety, Norwegian Veterinary Institute, 1433 Ås, Norway.
Ane Mohr OslandDepartment of Analysis and Diagnostics, Norwegian Veterinary Institute, 1433 Ås, Norway.
Lene K VestbyDepartment of Analysis and Diagnostics, Norwegian Veterinary Institute, 1433 Ås, Norway.ORCID 0000-0001-5387-130X
Norwegian Veterinary Institute · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biofilms are bacterial aggregates embedded in a self-produced, protective matrix. The biofilm lifestyle offers resilience to external threats such as the immune system, antimicrobials, and other treatments. It is therefore not surprising that biofilms have been observed to be present in a number of bacterial infections. This review describes biofilm-associated bacterial infections in most body systems of husbandry animals, including fish, as well as in sport and companion animals. The biofilms have been observed in the auditory, cardiovascular, central nervous, digestive, integumentary, reproductive, respiratory, urinary, and visual system. A number of potential roles that biofilms can play in disease pathogenesis are also described. Biofilms can induce or regulate local inflammation. For some bacterial species, biofilms appear to facilitate intracellular invasion. Biofilms can also obstruct the healing process by acting as a physical barrier. The long-term protection of bacteria in biofilms can contribute to chronic subclinical infections, Furthermore, a biofilm already present may be used by other pathogens to avoid elimination by the immune system. This review shows the importance of acknowledging the role of biofilms in animal bacterial infections, as this influences both diagnostic procedures and treatment.

Indexed as

animalsbiofilmendocarditisendometritismastitismeningoencephalitisrespiratory diseasesubclinical infectionswound infections

Identifiers

PMID36985183
PMCPMC10059901
OpenAlexW4322628673

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.