Evidence map›Paper›PMID 36986648›Full record

ArticlePharmaceutics2023

Discovery of New 1,4,6-Trisubstituted-1

Maria Georgiou, Nikolaos Lougiakis, Roxane Tenta, Katerina Gioti, Stavroula Baritaki, Lydia-Evangelia Gkaralea, Elisavet Deligianni, Panagiotis Marakos, Nicole Pouli, Dimitris Stellas

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Maria GeorgiouDivision of Pharmaceutical Chemistry, Department of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, Panepistimiopolis Zografou, 15771 Athens, Greece.ORCID 0000-0003-2480-1542
Nikolaos LougiakisDivision of Pharmaceutical Chemistry, Department of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, Panepistimiopolis Zografou, 15771 Athens, Greece.ORCID 0000-0003-0582-4415
Roxane TentaDepartment of Nutrition & Dietetics, School of Health Sciences and Education, Harokopio University, 17671 Athens, Greece.ORCID 0000-0002-4867-6945
Katerina GiotiDepartment of Nutrition & Dietetics, School of Health Sciences and Education, Harokopio University, 17671 Athens, Greece.
Stavroula BaritakiLaboratory of Experimental Oncology, Division of Surgery, School of Medicine, University of Crete, 71003 Heraklion, Greece.
Lydia-Evangelia GkaraleaInstitute of Chemical Biology, National Hellenic Research Foundation, 11635 Athens, Greece.
Elisavet DeligianniLaboratory of Experimental Oncology, Division of Surgery, School of Medicine, University of Crete, 71003 Heraklion, Greece.
Panagiotis MarakosDivision of Pharmaceutical Chemistry, Department of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, Panepistimiopolis Zografou, 15771 Athens, Greece.
Nicole PouliDivision of Pharmaceutical Chemistry, Department of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, Panepistimiopolis Zografou, 15771 Athens, Greece.
Dimitris StellasInstitute of Chemical Biology, National Hellenic Research Foundation, 11635 Athens, Greece.ORCID 0000-0002-7787-3921
National and Kapodistrian University of Athens · GRHarokopio University of Athens · GRNational Hellenic Research Foundation · GRUniversity of Crete · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purine analogues are important therapeutic tools due to their affinity to enzymes or receptors that are involved in critical biological processes. In this study, new 1,4,6-trisubstituted pyrazolo[3,4-

Indexed as

anticancer agentantiproliferative activitybreast cancerin vivopurine analoguespyrazolopyridine

Identifiers

PMID36986648
PMCPMC10057642
OpenAlexW4322630911

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.