Evidence map›Paper›PMID 36987305›Full record

ReviewPolymers2023

Scaffold Using Chitosan, Agarose, Cellulose, Dextran and Protein for Tissue Engineering-A Review.

Antony V Samrot, Mahendran Sathiyasree, Sadiq Batcha Abdul Rahim, Robinson Emilin Renitta, Kasirajan Kasipandian, Sivasuriyan Krithika Shree, Deenadhayalan Rajalakshmi, Nagarajan Shobana, Shanmugaboopathi Dhiva, Sasi Abirami and 4 more

Open access · goldAbstract readReview
In one paragraph

Review in Polymers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 45 citations in OpenAlex.

  1. Polysaccharides and carbohydrate polymers: innovations from nature to industry.Journal of the science of food and agriculture · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 2 countries.

Antony V SamrotSchool of Bioscience, Faculty of Medicine, Bioscience and Nursing, MAHSA University, Jalan SP2, Bandar Saujana Putra, Jenjarom 42610, Selangor, Malaysia.ORCID 0000-0001-9536-0567
Mahendran SathiyasreeDepartment of Biotechnology, School of Bio and Chemical Engineering Sathyabama Institute of Science and Technology, Chennai 600119, Tamil Nadu, India.
Sadiq Batcha Abdul RahimFaculty of Engineering, Built Environment and IT, MAHSA University, Jalan SP2, Bandar Saujana Putra, Jenjarom 42610, Selangor, Malaysia.
Robinson Emilin RenittaDepartment of Food Processing, Karunya Institute of Technology and Science, Coimbatore 641114, Tamil Nadu, India.
Kasirajan KasipandianFaculty of Engineering, Built Environment and IT, MAHSA University, Jalan SP2, Bandar Saujana Putra, Jenjarom 42610, Selangor, Malaysia.
Sivasuriyan Krithika ShreeDepartment of Biotechnology, School of Bio and Chemical Engineering Sathyabama Institute of Science and Technology, Chennai 600119, Tamil Nadu, India.
Deenadhayalan RajalakshmiDepartment of Biotechnology, School of Bio and Chemical Engineering Sathyabama Institute of Science and Technology, Chennai 600119, Tamil Nadu, India.
Nagarajan ShobanaDepartment of Biotechnology, School of Bio and Chemical Engineering Sathyabama Institute of Science and Technology, Chennai 600119, Tamil Nadu, India.
Shanmugaboopathi DhivaDepartment of Microbiology, Sree Narayana College, Alathur, Palakkad 678682, Kerala, India.
Sasi AbiramiDepartment of Microbiology, Kamaraj College, Thoothukudi, Affiliated to Manonmaniam Sundaranar University, Thoothukudi 628003, Tamil Nadu, India.
Sridevi VisvanathanUnit of Biochemistry, Faculty of Medicine, AIMST University, Semeling, Bedong 08100, Kedah Darul Aman, Malaysia.
Basanta Kumar MohantyFaculty of Medicine, Manipal University College Malaysia (MUCM), Jalan Padang Jambu, Bukit Baru 75150, Melaka, Malaysia.
Gokul Shankar SabesanFaculty of Medicine, Manipal University College Malaysia (MUCM), Jalan Padang Jambu, Bukit Baru 75150, Melaka, Malaysia.ORCID 0000-0002-5283-9241
Suresh V ChinniDepartment of Biochemistry, Faculty of Medicine, Bioscience and Nursing, MAHSA University, Jalan SP2, Bandar Saujana Putra, Jenjarom 42610, Selangor, Malaysia.ORCID 0000-0002-4697-2994
Mahsa University · MYSathyabama Institute of Science and Technology · INManipal University College Malaysia · MYAIMST University · MYKarunya University · INManonmaniam Sundaranar University · INNarayana Health · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biological macromolecules like polysaccharides/proteins/glycoproteins have been widely used in the field of tissue engineering due to their ability to mimic the extracellular matrix of tissue. In addition to this, these macromolecules are found to have higher biocompatibility and no/lesser toxicity when compared to synthetic polymers. In recent years, scaffolds made up of proteins, polysaccharides, or glycoproteins have been highly used due to their tensile strength, biodegradability, and flexibility. This review is about the fabrication methods and applications of scaffolds made using various biological macromolecules, including polysaccharides like chitosan, agarose, cellulose, and dextran and proteins like soy proteins, zein proteins, etc. Biopolymer-based nanocomposite production and its application and limitations are also discussed in this review. This review also emphasizes the importance of using natural polymers rather than synthetic ones for developing scaffolds, as natural polymers have unique properties, like high biocompatibility, biodegradability, accessibility, stability, absence of toxicity, and low cost.

Indexed as

nanotechnologynatural polymertissue engineering

Identifiers

PMID36987305
PMCPMC10054888
OpenAlexW4327975065

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.