Evidence map›Paper›PMID 36988349›Full record

ArticleActa biochimica et biophysica Sinica2023

miR-424(322)-5p targets

Yongqi Yue, Xinxin Feng, Yige Jia, Shujie Luo, Menglei Jiang, Jiandan Luo, Yonglin Hua, Jiyue Zhang, Yaqiu Lin, Jian Li and 1 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta biochimica et biophysica Sinica, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Yongqi YueCollege of Animal & Veterinary Sciences, Southwest Minzu University, Chengdu 610041, China.
Xinxin FengCollege of Animal & Veterinary Sciences, Southwest Minzu University, Chengdu 610041, China.
Yige JiaCollege of Animal & Veterinary Sciences, Southwest Minzu University, Chengdu 610041, China.
Shujie LuoCollege of Animal & Veterinary Sciences, Southwest Minzu University, Chengdu 610041, China.
Menglei JiangCollege of Animal & Veterinary Sciences, Southwest Minzu University, Chengdu 610041, China.
Jiandan LuoCollege of Animal & Veterinary Sciences, Southwest Minzu University, Chengdu 610041, China.
Yonglin HuaCollege of Animal & Veterinary Sciences, Southwest Minzu University, Chengdu 610041, China.
Jiyue ZhangCollege of Animal & Veterinary Sciences, Southwest Minzu University, Chengdu 610041, China.
Yaqiu LinCollege of Animal & Veterinary Sciences, Southwest Minzu University, Chengdu 610041, China.
Jian LiCollege of Animal & Veterinary Sciences, Southwest Minzu University, Chengdu 610041, China.
Yan XiongCollege of Animal & Veterinary Sciences, Southwest Minzu University, Chengdu 610041, China.
Southwest Minzu University · CNState Ethnic Affairs Commission · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The proliferation and differentiation of myoblasts are considered the key biological processes in muscle development and muscle-related diseases, in which the miRNAs involved remain incompletely understood. Previous research reported that miR-424(322)-5p is highly expressed in mouse skeletal muscle. Therefore, C2C12 cells are used as a model to clarify the effect of miR-424(322)-5p on the proliferation and differentiation of myoblasts. The data show that miR-424(322)-5p exhibits a decreasing trend upon myogenic differentiation. Overexpression of miR-424(322)-5p inhibits the proliferation of myoblasts, manifested by downregulation of proliferation marker genes (

Indexed as

MicroRNAsAnimalsCell DifferentiationCell LineCell ProliferationMiceMyoblastsPolycomb Repressive Complex 2Ezh1 protein, mouseMicroRNAsMIRN322 microRNA, mousePolycomb Repressive Complex 2differentiationmiR-424(322)-5pmyoblastproliferationskeletal muscle

Identifiers

PMID36988349
PMCPMC10160230
OpenAlexW4323033402

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.