Evidence map›Paper›PMID 36989465›Full record

ArticleJournal of clinical oncology : official journal of the American Society of Clinical Oncology2023

Smoking Cessation After Diagnosis of Kidney Cancer Is Associated With Reduced Risk of Mortality and Cancer Progression: A Prospective Cohort Study.

Mahdi Sheikh, Anush Mukeriya, Hana Zahed, Xiaoshuang Feng, Hilary A Robbins, Oxana Shangina, Vsevolod Matveev, Paul Brennan, David Zaridze

Open access · hybridAbstract read
In one paragraph

Article in Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

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  5. The preventable burden of tobacco-attributable cancer incidence in Catalonia (Spain) in 2024: a Bayesian approach.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Mahdi SheikhGenomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France.ORCID 0000-0003-3972-7824
Anush MukeriyaDepartment of Epidemiology, N.N. Blokhin National Medical Research Centre of Oncology, Moscow, Russia.ORCID 0000-0002-6847-9295
Hana ZahedGenomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France.ORCID 0000-0002-5731-8859
Xiaoshuang FengGenomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France.
Hilary A RobbinsGenomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France.ORCID 0000-0001-6041-6866
Oxana ShanginaDepartment of Epidemiology, N.N. Blokhin National Medical Research Centre of Oncology, Moscow, Russia.ORCID 0000-0003-2431-068X
Vsevolod MatveevDepartment of Urology, N.N. Blokhin National Medical Research Centre of Oncology, Moscow, Russia.ORCID 0000-0001-7748-9527
Paul BrennanGenomic Epidemiology Branch, International Agency for Research on Cancer (IARC/WHO), Lyon, France.
David ZaridzeDepartment of Epidemiology, N.N. Blokhin National Medical Research Centre of Oncology, Moscow, Russia.ORCID 0000-0002-2824-3704
Centre international de recherche sur le cancer · FR

Funding

World Health Organization 001
6 · The paper itself

Abstract

purposeTo investigate whether postdiagnosis smoking cessation may affect the risk of death and disease progression in patients with renal cell carcinoma (RCC) who smoked at the time of diagnosis.

methodsTwo hundred twelve patients with primary RCC were recruited between 2007 and 2016 from the Urological Department in N.N. Blokhin National Medical Research Center of Oncology, Moscow, Russia. Upon enrollment, a structured questionnaire was completed, and the patients were followed annually through 2020 to repeatedly assess their smoking status and disease progression. Survival probabilities and hazards for all-cause and cancer-specific mortality and disease progression were investigated using extended the Kaplan-Meier method, time-dependent Cox proportional hazards regression, and Fine-Gray competing-risk models.

resultsPatients were followed for a median of 8.2 years. During this time, 110 cases of disease progression, 100 total deaths, and 77 cancer-specific deaths were recorded. Eighty-four patients (40%) quit smoking after diagnosis. The total person-years at risk for this analysis were 748.2 for continuing smoking and 611.2 for quitting smoking periods. At 5 years of follow-up, both overall survival (85%

conclusionQuitting smoking after RCC diagnosis may significantly improve survival and reduce the risk of disease progression and cancer mortality among patients who smoke.

Indexed as

Carcinoma, Renal CellKidney NeoplasmsSmoking CessationDisease ProgressionHumansProspective StudiesRisk Factors

Identifiers

PMID36989465
PMCPMC10414692
OpenAlexW4361282959

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.