Evidence map›Paper›PMID 36992787›Full record

ArticleFrontiers in clinical diabetes and healthcare2022

Hypoglycemia event prediction from CGM using ensemble learning.

Jesper Fleischer, Troels Krarup Hansen, Simon Lebech Cichosz

Open access · goldFull text read
In one paragraph

Article in Frontiers in clinical diabetes and healthcare, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Artificial Intelligence to Diagnose Complications of Diabetes.Journal of diabetes science and technology · 2025
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Publicly Available Data Set Including Continuous Glucose Monitoring Data.Journal of diabetes science and technology · 2023
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jesper FleischerSteno Diabetes Center Aarhus, Aarhus, Denmark.
Troels Krarup HansenSteno Diabetes Center Aarhus, Aarhus, Denmark.
Simon Lebech CichoszDepartment of Health Science and Technology, Aalborg University, Aalborg, Denmark.
Steno Diabetes Center · DKAalborg University · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This work sought to explore the potential of using standalone continuous glucose monitor (CGM) data for the prediction of hypoglycemia utilizing a large cohort of type 1 diabetes patients during free-living. We trained and tested an algorithm for the prediction of hypoglycemia within 40 minutes on 3.7 million CGM measurements from 225 patients using ensemble learning. The algorithm was also validated using 11.5 million synthetic CGM data. The results yielded a receiver operating characteristic area under the curve (ROC AUC) of 0.988 and a precision-recall area under the curve (PR AUC) of 0.767. In an event-based analysis for predicting hypoglycemic events, the algorithm had a sensitivity of 90%, a lead-time of 17.5 minutes and a false-positive rate of 38%. In conclusion, this work demonstrates the potential of using ensemble learning to predict hypoglycemia, using only CGM data. This could help alarm patients of a future hypoglycemic event so countermeasures can be initiated.

Indexed as

blood glucose (BG)continuous glucose monitoring (CGM)Dexcom G4 platinumdiabetesevent predictionhypoglycaemiamachine learningtype 1 diabetes

Identifiers

PMID36992787
PMCPMC10012121
OpenAlexW4312059122

What Socratic holds

Textfull text, public
LicenceCC BY
measurements read29
identifiers read2
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.