ArticlebioRxiv : the preprint server for biology2023
split-intein Gal4 provides intersectional genetic labeling that is fully repressible by Gal80.
Ben Ewen-Campen, Haojiang Luan, Jun Xu, Rohit Singh, Neha Joshi, Tanuj Thakkar, Bonnie Berger, Benjamin H White, Norbert Perrimon
Open access · greenAbstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 1 citations in OpenAlex.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
9 authors at 3 institutions in 2 countries.
Ben Ewen-CampenThese authors contributed equally.
Haojiang LuanThese authors contributed equally.
Jun XuThese authors contributed equally.
Rohit SinghThese authors contributed equally.
Neha JoshiDepartment of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
Tanuj ThakkarDepartment of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
Bonnie BergerComputer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA 02139.
Benjamin H WhiteLaboratory of Molecular Biology, National Institute of Mental Health, NIH, Bethesda, MD 20892, USA.
Norbert PerrimonDepartment of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
Harvard University · USMassachusetts Institute of Technology · USNational Institute of Mental Health · US
Funding
Identifying Neural Substrates of Behavior in Drosophila MelanogasterZIAMH002800 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI WHITE, BENJAMIN H · 2009 to 2025
$29.2MFunctional genomics resources for the Drosophila - TR&D3P41GM132087 · NIGMS · HARVARD MEDICAL SCHOOL · PI MOHR, STEPHANIE E · 2019 to 2023
$6.8MUsing CRISPR technology to study the function of paralogous genesR24OD026435 · OD · HARVARD MEDICAL SCHOOL · PI BELLEN, HUGO J, PERRIMON, NORBERT · 2018 to 2021
$2.5MManifold representations and active learning for 21 st century biologyR35GM141861 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI BERGER, BONNIE · 2021 to 2025
$1.9MIntramural NIH HHS ZIA MH002800NIGMS NIH HHS P41 GM132087NIGMS NIH HHS R35 GM141861NIH HHS R24 OD026435
6 · The paper itselfAbstract
The split-Gal4 system allows for intersectional genetic labeling of highly specific cell-types and tissues in Significance statement: The split-Gal4 system allows
Identifiers
PMID36993523
PMCPMC10055387
OpenAlexW4360950949
What Socratic holds
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