SynthesisNeuroscience and biobehavioral reviews2023
The Big Five personality traits and allostatic load in middle to older adulthood: A systematic review and meta-analysis.
Synthesis in Neuroscience and biobehavioral reviews, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Personality and mortality risk: A systematic review and meta-analysis of longitudinal data.Journal of personality and social psychology · 2026Pooled it
- Allostatic Load and Cardiovascular Disease: A Systematic Review.American journal of preventive medicine · 2025Pooled it
- Personality and Risk of Arthritis in Six Longitudinal Samples.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024Pooled it
- Personality traits and mediating pathways to mortality risk: A systematic review.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2024Pooled it
- Personality predictors of dementia diagnosis and neuropathological burden: An individual participant data meta-analysis.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Pooled it
- Discrepancies in loneliness and social isolation predict cognitive impairment through chronic disease burden.Brain, behavior, & immunity - health · 2026Article
- Personality moderates immunological and functional consequences of caregiver burden.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026Article
- Do negative social ties accelerate aging in adults, or does aging erode social ties?Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Allostatic load, personality traits, and cancer risk: A prospective cohort study.Psychological medicine · 2026Article
- Big-5 personality traits as predictors of allostatic load in Latino Americans: a longitudinal study.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025Article
- Robust inference and widespread genetic correlates from a large-scale genetic association study of human personality.bioRxiv : the preprint server for biology · 2025Article
- Association between personality profiles and motoric cognitive risk syndrome in community-dwelling older adults: a person-centered approach.BMC psychiatry · 2025Article
- Allostatic load in non-medical and medical college students.BMC public health · 2025Article
- The status and influencing factors of death anxiety among Chinese college students under the COVID-19 pandemic: a cross-sectional study.BMC public health · 2025Article
- The relationship of coping style and social support variation to glucocorticoid metabolites in wild olive baboons (Papio anubis).Primates; journal of primatology · 2025Article
- Association between personality traits and concerns about falling among older patients: the mediating role of subjective age.Frontiers in public health · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Further understanding of the associations between personality traits and allostatic load (AL) may be important for predicting, addressing, and optimizing health outcomes. This review synthesized the existing literature reporting the association between the Big Five personality traits and AL in adults to identify the generalizability and robustness of relationships, potential mechanisms underlying the associations, and study characteristics that may be contributing to inconsistencies in the field. Published and unpublished empirical reports were included if at least one of the Big Five traits was examined and an AL index was constructed using at least two biomarkers in a sample of adults. The methodological plan and standardized coding guide were pre-registered and reported (https://osf.io/rxw5a). Based on 11 studies that met eligibility, meta-analysis of correlation coefficients indicated a small but significant positive association between neuroticism and AL, and small but significant inverse associations between both conscientiousness and openness with AL. This review identifies strengths and limitations within the field, as well as several avenues for future research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.