Evidence map›Paper›PMID 36997659›Full record

ArticleCommunications medicine2023

Prioritization of COVID-19 risk factors in July 2020 and February 2021 in the UK.

Sivateja Tangirala, Braden T Tierney, Chirag J Patel

Open access · goldAbstract read
In one paragraph

Article in Communications medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sivateja TangiralaDepartment of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0003-0305-471X
Braden T TierneyDepartment of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.
Chirag J PatelDepartment of Biomedical Informatics, Harvard Medical School, Boston, MA, USA. chirag_patel@hms.harvard.edu.ORCID http://orcid.org/0000-0002-8756-8525
Harvard University · US

Funding

Data science tools to identify robust exposure-phenotype associations for precision medicineR01ES032470 · NIEHS · HARVARD MEDICAL SCHOOL · PI MANRAI, ARJUN KUMAR, PATEL, CHIRAG J. · 2021 to 2025
$3.5M
Big Data Analysis of HIV Risk and Epidemiology in Sub-Saharan AfricaR01AI127250 · NIAID · STANFORD UNIVERSITY · PI BENDAVID, ERAN, PATEL, CHIRAG J. · 2017 to 2020
$2.7M
The confluence of extreme heat cold on the health and longevity of an Aging Population with Alzheimers and related DementiaRF1AG074372 · NIA · HARVARD MEDICAL SCHOOL · PI DOMINICI, FRANCESCA, ESTIRI, HOSSEIN · 2022 to 2023
$2.6M
NIAID NIH HHS R01 AI127250NIA NIH HHS RF1 AG074372NIEHS NIH HHS R01 ES032470
6 · The paper itself

Abstract

backgroundRisk for COVID-19 positivity and hospitalization due to diverse environmental and sociodemographic factors may change as the pandemic progresses.

methodsWe investigated the association of 360 exposures sampled before COVID-19 outcomes for participants in the UK Biobank, including 9268 and 38,837 non-overlapping participants, sampled at July 17, 2020 and February 2, 2021, respectively. The 360 exposures included clinical biomarkers (e.g., BMI), health indicators (e.g., doctor-diagnosed diabetes), and environmental/behavioral variables (e.g., air pollution) measured 10-14 years before the COVID-19 time periods.

resultsHere we show, for example, "participant having son and/or daughter in household" was associated with an increase in incidence from 20% to 32% (risk difference of 12%) between timepoints. Furthermore, we find age to be increasingly associated with COVID-19 positivity over time from Risk Ratio [RR] (per 10-year age increase) of 0.81 to 0.6 (hospitalization RR from 1.18 to 2.63, respectively).

conclusionsOur data-driven approach demonstrates that time of pandemic plays a role in identifying risk factors associated with positivity and hospitalization.

Identifiers

PMID36997659
PMCPMC10062272
OpenAlexW4362506011

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.