Evidence map›Paper›PMID 36999824›Full record

ArticleCancer medicine2023

Prevalence of cancer therapy cardiotoxicity as assessed by imaging procedures: A scoping review.

Valeria Cantoni, Roberta Green, Roberta Assante, Adriana D'Antonio, Francesca Maio, Emanuele Criscuolo, Roberto Bologna, Mario Petretta, Alberto Cuocolo, Wanda Acampa

Open access · goldAbstract readScoping Review
In one paragraph

Article in Cancer medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. An exploratory analysis of 24-h movement behaviors in individuals with cancer completing a 12-week resistance exercise intervention.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Valeria CantoniDepartment of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
Roberta GreenDepartment of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.ORCID 0000-0003-2659-2318
Roberta AssanteDepartment of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
Adriana D'AntonioDepartment of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
Francesca MaioDepartment of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
Emanuele CriscuoloDepartment of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
Roberto BolognaDepartment of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
Mario PetrettaIRCCS SYNLAB SDN, Naples, Italy.
Alberto CuocoloDepartment of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.ORCID 0000-0003-3431-7658
Wanda AcampaDepartment of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.ORCID 0000-0003-2187-4076
University of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdvances in treatment and optimization of chemotherapy protocols have greatly improved survival in cancer patients. Unfortunately, treatment can cause a reduction in left ventricular (LV) ejection fraction (EF) leading to cancer therapy-related cardiac dysfunction (CTRCD). We conducted a scoping review of published literature in order to identify and summarize the reported prevalence of cardiotoxicity evaluated by noninvasive imaging procedures in a wide-ranging of patients referred to cancer treatment as chemotherapy and/or radiation therapy.

methodsDifferent databases were checked (PubMed, Embase, and Web of Science) to identify studies published from January 2000 to June 2021. Articles were included if they reported data on LVEF evaluation in oncological patients treated with chemotherapeutic agents and/or radiotherapy, measured by echocardiography and/or nuclear or cardiac magnetic resonance imaging test, providing criteria of CTRCD evaluation such as the specific threshold for LVEF decrease.

resultsFrom 963 citations identified, 46 articles, comprising 6841 patients, met the criteria for the inclusion in the scoping review. The summary prevalence of CTRCD as assessed by imaging procedures in the studies reviewed was 17% (95% confidence interval, 14-20).

conclusionsThe results of our scoping review endorse the recommendations regarding imaging modalities to ensure identification of cardiotoxicity in patients undergoing cancer therapies. However, to improve patient management, more homogeneous CTRCD evaluation studies are required, reporting a detailed clinical assessment of the patient before, during and after treatment.

Indexed as

Antineoplastic AgentsHeart DiseasesNeoplasmsCardiotoxicityHumansPrevalenceVentricular Function, LeftAntineoplastic Agentscancer therapycardiotoxicityimaging

Identifiers

PMID36999824
PMCPMC10242861
OpenAlexW4362457753

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.