Evidence map›Paper›PMID 37001802›Full record

ArticleLife sciences2023

Plasma hydrogen sulfide, nitric oxide, and thiocyanate levels are lower during pregnancy compared to postpartum in a cohort of women from the Pacific northwest of the United States.

Maxwell B Zeigler, Emily E Fay, Sue L Moreni, Jennie Mao, Rheem A Totah, Mary F Hebert

Open access · greenAbstract read
In one paragraph

Article in Life sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Hydrogen sulfide and its role in female reproduction.Frontiers in veterinary science · 2024
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Maxwell B ZeiglerUniversity of Washington, Department of Medicinal Chemistry, Seattle, WA, USA. Electronic address: mzeigler@uw.edu.
Emily E FayUniversity of Washington, Department of Obstetrics and Gynecology, Seattle, WA, USA.
Sue L MoreniUniversity of Washington, Department of Obstetrics and Gynecology, Seattle, WA, USA.
Jennie MaoUniversity of Washington, Department of Obstetrics and Gynecology, Seattle, WA, USA.
Rheem A TotahUniversity of Washington, Department of Medicinal Chemistry, Seattle, WA, USA.
Mary F HebertUniversity of Washington, Department of Obstetrics and Gynecology, Seattle, WA, USA; University of Washington, Department of Pharmacy, Seattle, WA, USA.
University of Washington · US

Funding

Sudden cardiac arrest and circulating hydrogen sulfideR01HL146603 · NHLBI · UNIVERSITY OF WASHINGTON · PI SOTOODEHNIA, NONA, TOTAH, RHEEM ANGELA · 2019 to 2022
$2.9M
Circulating hydrogen sulfide, diabetes and diabetes-related cardiovascular diseaseR01HL163661 · NHLBI · UNIVERSITY OF WASHINGTON · PI LEMAITRE, ROZENN, TOTAH, RHEEM ANGELA · 2022 to 2025
$2.6M
Effects of Retinoids on CYP2D6 Activity and Variability in Special PopulationsR01GM124264 · NIGMS · UNIVERSITY OF WASHINGTON · PI HEBERT, MARY F · 2017 to 2020
$2.3M
NHLBI NIH HHS R01 HL146603NHLBI NIH HHS R01 HL163661NIGMS NIH HHS R01 GM124264
6 · The paper itself

Abstract

aimsPregnancy alters multiple physiological processes including angiogenesis, vasodilation, inflammation, and cellular redox, which are partially modulated by the gasotransmitters hydrogen sulfide (H MATERIALS AND

methodsPlasma was collected from 45 women at three points: 25-28 weeks gestation, 28-32 week gestation, and at ≥3 months postpartum. Plasma levels of H KEY

findingsNO and SCN SIGNIFICANCE: Previous reports demonstrated that the production of H

Indexed as

GasotransmittersHydrogen SulfideBridged Bicyclo CompoundsChromatography, LiquidFemaleHumansNitric OxidePostpartum PeriodPregnancyTandem Mass SpectrometryThiocyanatesUnited StatesBridged Bicyclo CompoundsGasotransmittersHydrogen SulfidemonobromobimaneNitric OxidethiocyanateThiocyanatesHydrogen sulfideHypertensionMethyl sulfideNitric oxidePostpartumPreeclampsiaPregnancyThiocyanate

Identifiers

PMID37001802
PMCPMC10133030
OpenAlexW4361274910

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.