ArticleApplied biochemistry and biotechnology2023
Antioxidant and Antidiabetic Activities, and UHPLC-ESI-QTOF-MS-Based Metabolite Profiling of an Endophytic Fungus Nigrospora sphaerica BRN 01 Isolated from Bauhinia purpurea L.
Article in Applied biochemistry and biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 10 citations in OpenAlex.
- Biological activities and metabolic profile of crude extracts from two Nigrospora sp. isolates.International microbiology : the official journal of the Spanish Society for Microbiology · 2026Article
- Secondary Metabolites from Diaporthe eres SK3, an Endophytic Fungus of Sellaginella kraussiana Sw. Collected from the Northeast Indian Hills, Exhibits Potential in Vitro Bioactivities.Current microbiology · 2026Article
- Diversity, bioactivities, and metabolomics of culturable endophytic fungi from the medicinal plantFrontiers in microbiology · 2026Article
- An Update of Fungal Endophyte Diversity and Strategies for Augmenting Therapeutic Potential of their Potent Metabolites: Recent Advancement.Applied biochemistry and biotechnology · 2025Review
- Elucidation of α-glucosidase inhibitory activity and UHPLC-ESI-QTOF-MS based metabolic profiling of endophytic fungiFrontiers in fungal biology · 2025Article
- Molecular characterization of a novel fusarivirus infecting the plant-pathogenic fungus Nigrospora sphaerica.Archives of virology · 2024Article
- Development and Validation of a Liquid Chromatography-Tandem Mass Spectrometry Method for Screening Potential Citrate Lyase Inhibitors from a Library of Marine Compounds.Marine drugs · 2024Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diabetes-associated postprandial hyperglycemia is a major risk factor in cardiovascular disease. Since enzyme α-glucosidase is primarily responsible for glucose release during digestion, inhibiting it mitigates post-meal spike in blood glucose level. Metabolites from endophytic fungi could be potential natural inhibitors of this enzyme. Endophytic fungi isolated from Bauhinia purpurea L. were screened for their potential antioxidant and antidiabetic activities. Ethyl acetate extract of Nigrospora sphaerica BRN 01 (NEE) displayed high antioxidant activity with an IC50 value of 9.72 ± 0.91 µg/ml for DPPH assay and ferric reducing antioxidant power (FRAP) of 1595 ± 0.23 µmol AAE g
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.