Evidence map›Paper›PMID 37005942›Full record

ReviewCell regeneration (London, England)2023

Molecular mechanisms of neurite regeneration and repair: insights from C. elegans and Drosophila.

Xiaofan Liu, Yuqing Zhao, Wei Zou

Abstract readReview
In one paragraph

Review in Cell regeneration (London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. The Repair Manual of a Fruit Fly Brain.International journal of molecular sciences · 2026
    Review
  2. Frontiers in cell and developmental biology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xiaofan Liu *The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, China.
Yuqing Zhao *The Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, China.
Wei ZouThe Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu, China. zouwei@zju.edu.cn.ORCID http://orcid.org/0000-0003-4885-7313

Funding

National Natural Science Foundation of China 31970919
6 · The paper itself

Abstract

The difficulties of injured and degenerated neurons to regenerate neurites and regain functions are more significant than in other body tissues, making neurodegenerative and related diseases hard to cure. Uncovering the secrets of neural regeneration and how this process may be inhibited after injury will provide insights into novel management and potential treatments for these diseases. Caenorhabditis elegans and Drosophila melanogaster are two of the most widely used and well-established model organisms endowed with advantages in genetic manipulation and live imaging to explore this fundamental question about neural regeneration. Here, we review the classical models and techniques, and the involvement and cooperation of subcellular structures during neurite regeneration using these two organisms. Finally, we list several important open questions that we look forward to inspiring future research.

Indexed as

AxotomyCaenorhabditis elegansDendrotomyDLK-1Drosophila melanogasterGenetic manipulationLive imagingNeurite regenerationNeurite repairSubcellular structures

Identifiers

PMID37005942
PMCPMC10067779

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.