Evidence map›Paper›PMID 37006297›Full record

ArticleFrontiers in immunology2023

Anti-cyclooxygenase, anti-glycation, and anti-skin aging effect of

Huiji Zhou, Luxian Zhou, Bo Li, Rongcai Yue

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05986799 (A Randomized, Controlled Trial of Efficacy of Amway Herbal Drink to Improve Skin Anti-aging), which is not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05986799 naunknown statusnot on this map

A Randomized, Controlled Trial of Efficacy of Amway Herbal Drink to Improve Skin Anti-aging

TypeinterventionalSponsorAmway (China) R&D CenterRan2023 to 2023Enrolled30ConditionsSkin Laxity, Skin LinesArmsAmway Herbal Drink, Placebo Drink
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Huiji ZhouAmway (Shanghai) Innovation and Science Co., Ltd, Shanghai, China.
Luxian ZhouShanghai Archgene Biotechnology Co., Ltd, Shanghai, China.
Bo LiAmway (Shanghai) Innovation and Science Co., Ltd, Shanghai, China.
Rongcai YueSchool of Pharmacy, Fujian Medical University, Fuzhou, Fujian, China.
Fujian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Methods: Antioxidant tests, including 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), the ferric reducing ability of plasma (FRAP), and intracellular reactive oxygen species (ROS) level analyses in primary human epidermal keratinocytes, anti-cyclooxygenase2 (COX-2) assay, anti-glycation assay (both fluorescent AGEs formation in a BSA fructose/glucose system and glycation cell assay), and anti-aging assay (quantification of collagen types I and III, and SA-β-gal staining assay) were conducted to determine the potential biological effects of DOF extracts and its major compounds. Ultra-performance liquid chromatography-electrospray ionisation-quadrupole-time-of-flight-mass spectrometry (UPLC-ESI-QTOF-MS/MS) was performed to investigate the composition of DOF extracts. Online antioxidant post-column bioassay tests were applied to rapidly screen major antioxidants in DOF extracts. Results and discussion: The aqueous extract of

Indexed as

AntioxidantsDendrobiumAgingBenzothiazolesCyclooxygenase 2FlowersGlucosidesHumansPhytochemicalsPlant ExtractsRutinSulfonic AcidsTandem Mass Spectrometry2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acidAntioxidantsBenzothiazolesCyclooxygenase 2GlucosidesPhytochemicalsPlant ExtractsRutinSulfonic Acidsanti-agingantioxidantDendrobium officinaleflavone di-C-glycosidesUPLC-ESI-qTOF-MS/MS

Identifiers

PMID37006297
PMCPMC10064984
OpenAlexW4327745349

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.