Evidence map›Paper›PMID 37013111›Full record

ArticleERJ open research2023

Conservative oxygen supplementation during helmet continuous positive airway pressure therapy in patients with COVID-19 and respiratory failure: a pilot study.

Alessandra Iacovelli, Maria Luisa Nicolardi, Valentina Baccolini, Federica Olmati, Ilenia Attilia, Pia Baiocchi, Letizia D'Antoni, Ilaria Menichini, Ambra Migliarini, Daniela Pellegrino and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ERJ open research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 73% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Alessandra IacovelliDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.ORCID https://orcid.org/0000-0002-7103-7842
Maria Luisa NicolardiDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.
Valentina BaccoliniDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.ORCID https://orcid.org/0000-0002-7873-7817
Federica OlmatiDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.
Ilenia AttiliaDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.
Pia BaiocchiDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.
Letizia D'AntoniDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.
Ilaria MenichiniDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.
Ambra MigliariniDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.
Daniela PellegrinoDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.
Angelo PetroianniDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.
Daniel PiamontiDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.ORCID https://orcid.org/0000-0003-4784-1950
Angela TramontanoDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.
Paolo VillariDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.
Paolo PalangeDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Rome, Italy.
Policlinico Umberto I · ITSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Respiratory failure is a severe complication in coronavirus disease 2019 (COVID-19) pneumonia that, in addition to oxygen therapy, may require continuous positive airway pressure (CPAP) support. It has been postulated that COVID-19 lung injury may share some features with those observed in hyperoxic acute lung injury. Thus, a correct target arterial oxygen tension ( Methods: This was a single-centre, historically controlled study of patients with severe respiratory failure due to COVID-19 pneumonia, receiving either conservative or nonconservative oxygen supplementation during helmet CPAP. A cohort receiving conservative oxygen supplementation was studied prospectively in which oxygen supplementation was administered with a target Results: 71 patients were included in the conservative cohort and 75 in the nonconservative cohort. Mortality rate was lower in the conservative cohort (22.5% Conclusions: In patients with COVID-19 and severe respiratory failure, conservative oxygen supplementation during helmet CPAP was associated with improved survival, lower ICU admission rate and less new-onset organ failure.

Identifiers

PMID37013111
PMCPMC9790093
OpenAlexW4312190739

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.