Evidence map›Paper›PMID 37014409›Full record

ReviewEuropean radiology2023

The technical development of photon-counting detector CT.

Cynthia H McCollough, Kishore Rajendran, Shuai Leng, Lifeng Yu, Joel G Fletcher, Karl Stierstorfer, Thomas G Flohr

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in European radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Obese patient imaging: Potential dose reduction with photon-counting CT.Journal of applied clinical medical physics · 2026
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Cardiac imaging using photon counting CT - benefits, challenges and prospects.The international journal of cardiovascular imaging · 2026
    Review
  15. Review
  16. Article
  17. Review
  18. Obese patient imaging: improved dose efficiency with photon-counting CT.medRxiv : the preprint server for health sciences · 2025
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Cynthia H McColloughDepartment of Radiology, Mayo Clinic, Rochester, MN, USA. mccollough.cynthia@mayo.edu.ORCID http://orcid.org/0000-0002-5346-332X
Kishore RajendranDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Shuai LengDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Lifeng YuDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Joel G FletcherDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Karl StierstorferSiemens Healthineers, Forchheim, Germany.
Thomas G FlohrSiemens Healthineers, Forchheim, Germany.

Funding

Comprehensive characterization of coronary atherosclerotic disease using photon-counting-detector dual-source CT and its impact on patient managementR01EB028590 · NIBIB · MAYO CLINIC ROCHESTER · PI LENG, SHUAI, MCCOLLOUGH, CYNTHIA H · 2020 to 2023
$2.6M
NIBIB NIH HHS r01 EB028590NIBIB NIH HHS R01 EB028590
6 · The paper itself

Abstract

Since 1971 and Hounsfield's first CT system, clinical CT systems have used scintillating energy-integrating detectors (EIDs) that use a two-step detection process. First, the X-ray energy is converted into visible light, and second, the visible light is converted to electronic signals. An alternative, one-step, direct X-ray conversion process using energy-resolving, photon-counting detectors (PCDs) has been studied in detail and early clinical benefits reported using investigational PCD-CT systems. Subsequently, the first clinical PCD-CT system was commercially introduced in 2021. Relative to EIDs, PCDs offer better spatial resolution, higher contrast-to-noise ratio, elimination of electronic noise, improved dose efficiency, and routine multi-energy imaging. In this review article, we provide a technical introduction to the use of PCDs for CT imaging and describe their benefits, limitations, and potential technical improvements. We discuss different implementations of PCD-CT ranging from small-animal systems to whole-body clinical scanners and summarize the imaging benefits of PCDs reported using preclinical and clinical systems. KEY POINTS: • Energy-resolving, photon-counting-detector CT is an important advance in CT technology. • Relative to current energy-integrating scintillating detectors, energy-resolving, photon-counting-detector CT offers improved spatial resolution, improved contrast-to-noise ratio, elimination of electronic noise, increased radiation and iodine dose efficiency, and simultaneous multi-energy imaging. • High-spatial-resolution, multi-energy imaging using energy-resolving, photon-counting-detector CT has been used in investigations into new imaging approaches, including multi-contrast imaging.

Indexed as

IodineTomography, X-Ray ComputedAnimalsPhantoms, ImagingPhotonsX-RaysIodineHumansIodinePhotonsRadiation dosageTomography, X-ray computed

Identifiers

PMID37014409
PMCPMC10330290

What Socratic holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.