Evidence map›Paper›PMID 37015409›Full record

ArticleIEEE transactions on bio-medical engineering2023

A Wearable Fiber-Free Optical Sensor for Continuous Monitoring of Cerebral Blood Flow in Freely Behaving Mice.

Xuhui Liu, Daniel A Irwin, Chong Huang, Yutong Gu, Li Chen, Kevin D Donohue, Lei Chen, Guoqiang Yu

Abstract read
In one paragraph

Article in IEEE transactions on bio-medical engineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xuhui Liu
Daniel A Irwin
Chong Huang
Yutong Gu
Li Chen
Kevin D Donohue
Lei Chen
Guoqiang Yu

Funding

Noninvasive Noncontact High-Density Optical Imaging of Neonatal Intraventricular HemorrhageR01HD101508 · NICHD · UNIVERSITY OF KENTUCKY · PI YU, GUOQIANG · 2020 to 2024
$2.7M
Perioperative Diffuse Optical Imaging of Tissue Blood Flow and Oxygenation for Optimization of Mastectomy Skin Flap ViabilityR01EB028792 · NIBIB · UNIVERSITY OF KENTUCKY · PI YU, GUOQIANG · 2020 to 2024
$1.9M
High-density optical tomography of cerebral blood flow and metabolism in small animalsR41NS122722 · NINDS · BIOPTICSTECHNOLOGY, LLC · PI YU, GUOQIANG · 2021 to 2022
$688k
Continuous and Longitudinal Monitoring of Cerebral Blood Flow and Metabolism in Freely Moving RodentsR56NS117587 · NINDS · UNIVERSITY OF KENTUCKY · PI YU, GUOQIANG · 2020 to 2020
$613k
A Multiscale Multimodal Diffuse Optical Device for Early Detection of Preclinical Alzheimer’s DiseaseR21HD091118 · NICHD · UNIVERSITY OF KENTUCKY · PI YU, GUOQIANG · 2018 to 2019
$568k
NIBIB NIH HHS R01 EB028792NICHD NIH HHS R01 HD101508NICHD NIH HHS R21 HD091118NINDS NIH HHS R41 NS122722NINDS NIH HHS R56 NS117587
6 · The paper itself

Abstract

objectiveWearable technologies for functional brain monitoring in freely behaving subjects can advance our understanding of cognitive processing and adaptive behavior. Existing technologies are lacking in this capability or need procedures that are invasive and/or otherwise impede brain assessments during social behavioral conditions, exercise, and sleep.

methodsIn response a complete system was developed to combine relative cerebral blood flow (rCBF) measurement, O RESULTS AND

conclusionsSignificant correlations were found between measurements with the new DSCF design and an optical standard. The system successfully detected rCBF responses to CO SIGNIFICANCE: Collecting rCBF and activity information together during natural behaviors provides realistic physiological results and opens the path to exploring their correlations with pathophysiological conditions.

Indexed as

Carbon DioxideWearable Electronic DevicesAnimalsBrainCerebrovascular CirculationConsciousnessMiceCarbon Dioxide

Identifiers

PMID37015409
PMCPMC10542964

What Socratic holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.