Evidence map›Paper›PMID 37016419›Full record

ReviewVirology journal2023

Progress in the study of parvovirus entry pathway.

Jiuming Shi, Yifeng Pei, Qian Yu, Hao Dong

Abstract readReview
In one paragraph

Review in Virology journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jiuming ShiCollege of Life Sciences, Jilin Agricultural University, Changchun, 130118, Jilin Province, China.
Yifeng PeiCollege of Life Sciences, Jilin Agricultural University, Changchun, 130118, Jilin Province, China.
Qian YuCollege of Life Sciences, Jilin Agricultural University, Changchun, 130118, Jilin Province, China.
Hao DongCollege of Life Sciences, Jilin Agricultural University, Changchun, 130118, Jilin Province, China. donghao@jlau.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A group of DNA viruses called parvoviruses that have significant effects on cancer therapy and genetic engineering applications. After passing through the cell membrane to reach the cytosol, it moves along the microtubule toward the nuclear membrane. The nuclear localization signal (NLS) is recognized by importin-beta (impβ) and other proteins from the complex outside the nuclear membrane and binds to enter the nucleus via the nuclear pore complex (NPC). There are two main pathways for viruses to enter the nucleus. The classical pathway is through the interaction of imp α and impβ with NLS via NPC. The other is the NPC mediated by the combination of impβ and it. While the capsid is introduced into the nucleus through classical nuclear transduction, there is also a transient nuclear membrane dissolution leading to passive transport into the nucleus, which has been proposed in recent years. This article mainly discusses several nuclear entry pathways and related proteins, providing a reference for subsequent research on viral entry pathways.

Indexed as

Parvoviridae InfectionsParvovirusActive Transport, Cell Nucleusalpha Karyopherinsbeta KaryopherinsCell NucleusHumansNuclear EnvelopeNuclear Localization Signalsalpha Karyopherinsbeta KaryopherinsNuclear Localization SignalsImp β participationNuclear membrane permeabilityNuclear pathwayParvovirus

Identifiers

PMID37016419
PMCPMC10072039

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.