Evidence map›Paper›PMID 37018198›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

GINS4 suppresses ferroptosis by antagonizing p53 acetylation with Snail.

Ling Chen, Qidong Cai, Rui Yang, Haiyan Wang, Huli Ling, Tiansheng Li, Na Liu, Zuli Wang, Jingyue Sun, Tania Tao and 6 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
16.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 61 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Mechanism of Ferroptosis and Its Role in Disease Development.International journal of biological sciences · 2025
    Review
  17. The Role of Redox Environment in Tumors.Current medicinal chemistry · 2025
    Review
  18. Article
  19. Article
  20. Comprehensive analysis ofTranslational andrology and urology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Ling ChenHunan Key Laboratory of Cancer Metabolism, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha Hunan 410031, China.ORCID 0000-0003-4476-9711
Qidong CaiDepartment of Thoracic Surgery, Hunan Key Laboratory of Early Diagnosis and Precision Therapy in Lung Cancer, Second Xiangya Hospital, Central South University, Changsha Hunan 410011, China.
Rui YangHunan Key Laboratory of Cancer Metabolism, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha Hunan 410031, China.
Haiyan WangHunan Key Laboratory of Cancer Metabolism, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha Hunan 410031, China.
Huli LingHunan Key Laboratory of Cancer Metabolism, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha Hunan 410031, China.
Tiansheng LiHunan Key Laboratory of Cancer Metabolism, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha Hunan 410031, China.
Na LiuHunan International Scientific and Technological Cooperation Base of Brain Tumor Research, Xiangya Hospital, Central South University, Changsha Hunan 410008, China.
Zuli WangHunan Key Laboratory of Cancer Metabolism, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha Hunan 410031, China.
Jingyue SunHunan Key Laboratory of Cancer Metabolism, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha Hunan 410031, China.
Tania TaoKey Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education, National Health Commission Key Laboratory of Carcinogenesis, Cancer Research Institute, Central South University, Changsha Hunan 410078, China.
Ying ShiHunan Key Laboratory of Cancer Metabolism, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha Hunan 410031, China.
Ya CaoHunan Key Laboratory of Cancer Metabolism, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha Hunan 410031, China.
Xiang WangDepartment of Thoracic Surgery, Hunan Key Laboratory of Early Diagnosis and Precision Therapy in Lung Cancer, Second Xiangya Hospital, Central South University, Changsha Hunan 410011, China.
Desheng XiaoDepartment of Pathology, Xiangya Hospital, Central South University, Changsha Hunan 410008, China.
Shuang LiuDepartment of Oncology, Institute of Medical Sciences, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha Hunan 410008, China.
Yongguang TaoHunan Key Laboratory of Cancer Metabolism, Hunan Cancer Hospital and The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha Hunan 410031, China.ORCID 0000-0003-2354-5321
Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ferroptosis is an iron-dependent oxidative, nonapoptotic form of regulated cell death caused by the destruction of redox homeostasis. Recent studies have uncovered complex cellular networks that regulate ferroptosis. GINS4 is a promoter of eukaryotic G

Indexed as

FerroptosisAcetylationCell CycleChromosomal Proteins, Non-HistoneHumansOxidation-ReductionSnail Family Transcription FactorsTumor Suppressor Protein p53Chromosomal Proteins, Non-HistoneGINS4 protein, humanSnail Family Transcription FactorsTumor Suppressor Protein p53

Identifiers

PMID37018198
PMCPMC10104543
OpenAlexW4362601422

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.