Evidence map›Paper›PMID 37019608›Full record

ArticleCold Spring Harbor protocols2023

Methods for Exploring the Circuit Basis of Ethanol-Induced Changes in

Kavin M Nuñez, Jamie L Catalano, Kristin M Scaplen, Karla R Kaun

Open access · greenAbstract read
In one paragraph

Article in Cold Spring Harbor protocols, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Ethanol Behavioral Responses inCold Spring Harbor protocols · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kavin M NuñezMolecular Pharmacology and Physiology Graduate Program, Brown University, Providence, Rhode Island 02912, USA.
Jamie L CatalanoMolecular Pharmacology and Physiology Graduate Program, Brown University, Providence, Rhode Island 02912, USA.
Kristin M ScaplenDepartment of Psychology, Bryant University, Smithfield, Rhode Island 02917, USA.
Karla R KaunDepartment of Neuroscience, Brown University, Providence, Rhode Island 02912, USA karla_kaun@brown.edu.
Brown University · US

Funding

Training CoreP20GM103430 · NIGMS · UNIVERSITY OF RHODE ISLAND · PI Christopher Lee Hemme · 2012 to 2026
$63.6M
The neural basis of sequential control in human and non-human primatesP20GM103645 · NIGMS · BROWN UNIVERSITY · PI SANES, JEROME N · 2013 to 2022
$22.9M
Notch-dependent microcircuit regulaton of alcohol reward memoryR01AA024434 · NIAAA · BROWN UNIVERSITY · PI KAUN, KARLA R. · 2016 to 2025
$3.9M
CSHL Neurobiology of Drosophila CourseR13DA034437 · NIDA · COLD SPRING HARBOR LABORATORY · PI STEWART, DAVID J. · 2012 to 2016
$175k
NIAAA NIH HHS R01 AA024434NIDA NIH HHS R13 DA034437NIGMS NIH HHS P20 GM103430NIGMS NIH HHS P20 GM103645
6 · The paper itself

Abstract

Locomotion is a behavioral readout that can be used to understand responses to specific stimuli or perturbations. The fly Group Activity Monitor (flyGrAM) provides a high-throughput and high-content readout of the acute stimulatory and sedative effects of ethanol. The flyGrAM system is adaptable and seamlessly introduces thermogenetic or optogenetic stimulation to dissect neural circuits underlying behavior and tests responses to other volatilized stimuli (humidified air, odorants, anesthetics, vaporized drugs of abuse, etc.). The automated quantification and readout of activity provide users with a real-time representation of the group activity within each chamber throughout the experiment, helping users to quickly determine proper ethanol doses and duration, run behavioral screens, and plan follow-up experiments.

Indexed as

DrosophilaEthanolAnimalsBehavior, AnimalLocomotionOptogeneticsEthanol

Identifiers

PMID37019608
PMCPMC10551048
OpenAlexW4362657698

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.