ArticleBMC genomics2023
Genome-wide identification of the geranylgeranyl pyrophosphate synthase (GGPS) gene family involved in chlorophyll synthesis in cotton.
Article in BMC genomics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 21 citations in OpenAlex.
- Enhancing Geranylgeranyl Pyrophosphate Supply in Engineered Cyanobacteria for Improved Production of Natural Pigments and Terpenoid Precursors.International journal of molecular sciences · 2026Article
- TkNACs Heterodimerization and Methyl Jasmonate Signaling Synergistically Mediate Root Development inPlants (Basel, Switzerland) · 2026Article
- Delonix regia pollen extract enhances growth and bioactive compound production in Coriandrum sativum by upregulating key biosynthetic genes.Scientific reports · 2026Article
- Genomic analysis of terpene synthase family and characterization of ent-kaurene synthase in Chenopodium quinoa.Molecular genetics and genomics : MGG · 2025Article
- Genome-Wide Identification of the Potato GGPS Gene Family and Analysis of Its Response to Abiotic Stress.Genes · 2025Article
- A Comprehensive Analysis In Silico ofPlants (Basel, Switzerland) · 2024Article
- Genome-Wide Identification of the Geranylgeranyl Pyrophosphate Synthase (GGPS) Gene Family Associated with Natural Rubber Synthesis inPlants (Basel, Switzerland) · 2024Article
- Pan-genome analysis of GT64 gene family and expression response to Verticillium wilt in cotton.BMC plant biology · 2024Article
- Genome-wide identification of JAZ gene family members in autotetraploid cultivated alfalfa (Medicago sativa subsp. sativa) and expression analysis under salt stress.BMC genomics · 2024Article
- Overexpression of theFrontiers in plant science · 2024Article
- Article
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Authors and funding
12 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundGeranylgeranyl pyrophosphate synthase (GGPS) is a structural enzyme of the terpene biosynthesis pathway that is involved in regulating plant photosynthesis, growth and development, but this gene family has not been systematically studied in cotton.
resultsIn the current research, genome-wide identification was performed, and a total of 75 GGPS family members were found in four cotton species, Gossypium hirsutum, Gossypium barbadense, Gossypium arboreum and Gossypium raimondii. The GGPS genes were divided into three subgroups by evolutionary analysis. Subcellular localization prediction showed that they were mainly located in chloroplasts and plastids. The closely related GGPS contains a similar gene structure and conserved motif, but some genes are quite different, resulting in functional differentiation. Chromosome location analysis, collinearity and selection pressure analysis showed that many fragment duplication events occurred in GGPS genes. Three-dimensional structure analysis and conservative sequence analysis showed that the members of the GGPS family contained a large number of α-helices and random crimps, and all contained two aspartic acid-rich domains, DDxxxxD and DDxxD (x is an arbitrary amino acid), suggesting its key role in function. Cis-regulatory element analysis showed that cotton GGPS may be involved in light response, abiotic stress and other processes. A GGPS gene was silenced successfully by virus-induced gene silencing (VIGS), and it was found that the chlorophyll content in cotton leaves decreased significantly, suggesting that the gene plays an important role in plant photosynthesis.
conclusionsIn total, 75 genes were identified in four Gossypium species by a series of bioinformatics analysis. Gene silencing from GGPS members of G. hirsutum revealed that GGPS plays an important regulatory role in photosynthesis. This study provides a theoretical basis for the biological function of GGPS in cotton growth and development.
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