Evidence map›Paper›PMID 37025253›Full record

ReviewMedComm2023

Metal-based nanomaterials and nanocomposites as promising frontier in cancer chemotherapy.

Sunil Kumar, Monu Kumar Shukla, Abhishek Kumar Sharma, Gururaj K Jayaprakash, Rajiv K Tonk, Dinesh K Chellappan, Sachin Kumar Singh, Kamal Dua, Faheem Ahmed, Sanjib Bhattacharyya and 1 more

Abstract readReview
In one paragraph

Review in MedComm, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sunil KumarDepartment of Pharmaceutical Chemistry School of Pharmaceutical Sciences Shoolini University Solan Himachal Pradesh India.ORCID https://orcid.org/0000-0003-1203-7524
Monu Kumar ShuklaDepartment of Pharmaceutical Chemistry School of Pharmaceutical Sciences Shoolini University Solan Himachal Pradesh India.
Abhishek Kumar SharmaSchool of Pharmaceutical Sciences Shoolini University Solan Himachal Pradesh India.
Gururaj K JayaprakashDepartment of Chemistry Nitte Meenakshi Institute of Technology Bangalore Karnataka India.
Rajiv K TonkSchool of Pharmaceutical Sciences Delhi Pharmaceutical Sciences and Research University New Delhi Delhi India.
Dinesh K ChellappanDepartment of Life Sciences International Medical University Kuala Lumpur Malaysia.
Sachin Kumar SinghSchool of Pharmaceutical Sciences Lovely Professional University Phagwara Punjab India.
Kamal DuaDiscipline of Pharmacy, Graduate School of Health University of Technology Sydney Ultimo New South Wales Australia.
Faheem AhmedDepartment of Physics College of Science King Faisal University Al-Hofuf Al-Ahsa Saudi Arabia.
Sanjib BhattacharyyaInstitute of Science Nirma University Ahmedabad Gujarat India.
Deepak KumarDepartment of Pharmaceutical Chemistry School of Pharmaceutical Sciences Shoolini University Solan Himachal Pradesh India.ORCID https://orcid.org/0000-0003-2241-0054

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is a disease associated with complex pathology and one of the most prevalent and leading reasons for mortality in the world. Current chemotherapy has challenges with cytotoxicity, selectivity, multidrug resistance, and the formation of stemlike cells. Nanomaterials (NMs) have unique properties that make them useful for various diagnostic and therapeutic purposes in cancer research. NMs can be engineered to target cancer cells for early detection and can deliver drugs directly to cancer cells, reducing side effects and improving treatment efficacy. Several of NMs can also be used for photothermal therapy to destroy cancer cells or enhance immune response to cancer by delivering immune-stimulating molecules to immune cells or modulating the tumor microenvironment. NMs are being modified to overcome issues, such as toxicity, lack of selectivity, increase drug capacity, and bioavailability, for a wide spectrum of cancer therapies. To improve targeted drug delivery using nano-carriers, noteworthy research is required. Several metal-based NMs have been studied with the expectation of finding a cure for cancer treatment. In this review, the current development and the potential of plant and metal-based NMs with their effects on size and shape have been discussed along with their more effective usage in cancer diagnosis and treatment.

Indexed as

cancerchemotherapynanocompositesnanomaterialsnanomedicine

Identifiers

PMID37025253
PMCPMC10072971

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.