Evidence map›Paper›PMID 37026064›Full record

ArticleOpen veterinary journal2023

Genotyping of cows by LHCGR, FSHR loci, and determination of the level of ovulation depending on the expression of the studied genes.

Yktiyar Sarybayev, Yessengali Ussenbekov, Orynbassar Turebekov, Bekbolat Turumbetov, Ibragim Tutkyshbay

Abstract read
In one paragraph

Article in Open veterinary journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yktiyar SarybayevDepartment of Obstetrics, Surgery and Biotechnology of Animal Reproduction, Kazakh National Agrarian Research University, Almaty, Republic of Kazakhstan.
Yessengali UssenbekovDepartment of Obstetrics, Surgery and Biotechnology of Animal Reproduction, Kazakh National Agrarian Research University, Almaty, Republic of Kazakhstan.
Orynbassar TurebekovDepartment of Obstetrics, Surgery and Biotechnology of Animal Reproduction, Kazakh National Agrarian Research University, Almaty, Republic of Kazakhstan.
Bekbolat TurumbetovDepartment of Veterinary Medicine, Mukhtar Auezov South Kazakhstan University, Shymkent, Republic of Kazakhsta.
Ibragim TutkyshbayDepartment of Veterinary Medicine, Mukhtar Auezov South Kazakhstan University, Shymkent, Republic of Kazakhsta.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Genotyping offers a promising avenue for identifying the healthy reproductive system in cows. The healthy reproductive system in cows is determined by measuring the level of ovulation and by identifying the type polymorphism of specific genes. Aim: The aim of the article is to explore how polymorphism of follicle stimulating hormone Receptor (FSHR) and luteinizing hormone/choriogonadotropin receptor (LHCGR) genes affect the reproduction trait of Holstein cows. Methods: Here we define a reproducible protocol to genotype and identify the polymorphism in specific genes from the extracted DNA of cows. Results: The results of genotyping showed that the only C allele (CC genotype) was observed in 100% of cows at the LHCGR locus, and three genotypes were observed at the FSHR locus (CC-67.74%, CG-9.03%, GG-23.22%). In cows with the CC genotype at the FSHR locus, the hormone concentration during ovulation was 1.1-2.5 ng/ml, which is within the physiological range for healthy reproduction. Conclusion: Cows with the CC genotype at the FSHR locus have a healthy course of the ovulation process, therefore good reproduction.

Indexed as

Polymorphism, GeneticReceptors, FSHAnimalsCattleFemaleGenotypeOvulationPhenotypeReceptors, FSHFSHRGenotypingLHCGROvulationPolymorphism

Identifiers

PMID37026064
PMCPMC10072843

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.