Evidence mapPaperPMID 37033264Full record

ArticleFrontiers in endocrinology2023

High prevalence of sarcopenia and myosteatosis in patients undergoing hemodialysis.

Chen Fu, Dong Yan, Ling Wang, Fangfang Duan, Dalong Gu, Ning Yao, Mingke Sun, Di Wang, Xuya Lin, Yanglei Wu and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Chen FuDepartment of Nephrology, Beijing Jishuitan Hospital, Beijing, China.
Dong YanDepartment of Radiology, Beijing Jishuitan Hospital, Beijing, China.
Ling WangDepartment of Radiology, Beijing Jishuitan Hospital, Beijing, China.
Fangfang DuanClinical Epidemiology Research Center, Beijing Jishuitan Hospital, Beijing, China.
Dalong GuDepartment of Radiology, Beijing Jishuitan Hospital, Beijing, China.
Ning YaoDepartment of Radiology, Beijing Jishuitan Hospital, Beijing, China.
Mingke SunDepartment of Radiology, Beijing Jishuitan Hospital, Beijing, China.
Di WangDepartment of Nephrology, Beijing Jishuitan Hospital, Beijing, China.
Xuya LinDepartment of Nephrology, Beijing Jishuitan Hospital, Beijing, China.
Yanglei WuMR Collaboration, Siemens Healthineers Ltd., Beijing, China.
Xiaofei WangDepartment of Nephrology, Beijing Jishuitan Hospital, Beijing, China.
Xiaoguang ChengDepartment of Radiology, Beijing Jishuitan Hospital, Beijing, China.
Dongliang ZhangDepartment of Nephrology, Beijing Jishuitan Hospital, Beijing, China.
Beijing Jishuitan Hospital · CNPeking University · CNSiemens (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and purpose: Sarcopenia is highly prevalent (28.5-40.3%) in patients undergoing hemodialysis and leads to poor clinical outcomes. However, the association between muscle quality and sarcopenia in patients receiving hemodialysis remains unclear. Therefore, we aimed to explore the association between muscle cross-sectional area (CSA) and proton-density fat-fraction (PDFF) in patients with sarcopenia undergoing hemodialysis. Methods: Seventy-six patients undergoing hemodialysis for > 3 months were enrolled. Their handgrip strength (HGS), short physical performance battery (SPPB) performance, and appendicular skeletal muscle mass index (ASMI) were measured. Sarcopenia was defined using the Asian Working Group for Sarcopenia 2019 consensus update. All patients underwent quantitative magnetic resonance imaging. CSA and PDFF were measured for the thigh, trunk, and gluteus muscles. Results: The prevalence of probable, confirmed, and severe sarcopenia in this study was 73.7%, 51.3%, and 22.4%, respectively. Older age (OR: 1.061, Conclusion: Our findings demonstrate the high prevalence of sarcopenia and myosteatosis in patients undergoing hemodialysis and might trigger a paradigm shift in intervention strategies for patients receiving hemodialysis.

Indexed as

SarcopeniaHand StrengthHumansMuscle, SkeletalPrevalenceRenal Dialysishand-grip strengthhemodialysismuscle cross-sectional areamyosteatosisproton-density fat-fractionquantitative MRIsarcopenia

Identifiers

PMID37033264
PMCPMC10076821
OpenAlexW4360616512

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.