ArticleResearch square2023
Transcription-replication interactions reveal principles of bacterial genome regulation.
Andrew W Pountain, Peien Jiang, Tianyou Yao, Ehsan Homaee, Yichao Guan, Magdalena Podkowik, Bo Shopsin, Victor J Torres, Ido Golding, Itai Yanai
Abstract readPreprint
In one paragraphArticle in Research square, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
10 authors.
Andrew W PountainInstitute for Systems Genetics, NYU Grossman School of Medicine, New York, NY USA.
Peien JiangInstitute for Systems Genetics, NYU Grossman School of Medicine, New York, NY USA.
Tianyou YaoDepartment of Physics, University of Illinois at Urbana Champaign, Urbana, IL USA.
Ehsan HomaeeDepartment of Physics, University of Illinois at Urbana Champaign, Urbana, IL USA.
Yichao GuanDepartment of Physics, University of Illinois at Urbana Champaign, Urbana, IL USA.
Magdalena PodkowikDepartment of Medicine, Division of Infectious Diseases, NYU Grossman School of Medicine, New York, NY, USA.
Bo ShopsinDepartment of Medicine, Division of Infectious Diseases, NYU Grossman School of Medicine, New York, NY, USA.
Funding
Spatiotemporal analysis of gene regulatory programs associated with GBS infection during pregnancyR01AI143290 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI RATNER, ADAM JONATHAN, YANAI, ITAI · 2019 to 2023
$3.8MHost-pathogen interactions during hospital adaptation of MRSAR01AI137336 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SHOPSIN, BO, YANAI, ITAI · 2019 to 2022
$3.3MILLUMINATING CELLULAR INDIVIDUALITY THROUGH BACTERIOPHAGE INFECTION (2nd Period)R35GM140709 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI Ido Golding · 2021 to 2026
$2.4MComputational framework for analyzing and annotating single bacterium RNA-Seq dataR21AI169350 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI YANAI, ITAI · 2022 to 2023
$466kNIAID NIH HHS R01 AI137336NIAID NIH HHS R01 AI143290NIAID NIH HHS R21 AI169350NIGMS NIH HHS R35 GM140709
6 · The paper itselfAbstract
Organisms determine the transcription rates of thousands of genes through a few modes of regulation that recur across the genome
Identifiers
PMID37034646
PMCPMC10081379
What Socratic holds
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