Evidence map›Paper›PMID 37035256›Full record

ArticleFrontiers in synaptic neuroscience2023

The effect of single-cell knockout of Fragile X Messenger Ribonucleoprotein on synaptic structural plasticity.

Marie Gredell, Ju Lu, Yi Zuo

Open access · goldAbstract read
In one paragraph

Article in Frontiers in synaptic neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Astrocytes in fragile X syndrome.Frontiers in cellular neuroscience · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Marie GredellDepartment of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, Santa Cruz, CA, United States.
Ju LuDepartment of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, Santa Cruz, CA, United States.
Yi ZuoDepartment of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, Santa Cruz, CA, United States.
University of California, Santa Cruz · US

Funding

Fronto-insular network in cognitive-affective interactions during decision-makingR01MH127737 · NIMH · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI Kuan Hong Wang, Yi Zuo · 2022 to 2026
$2.8M
Identifying signatures of brain aging through heterochronic blood exchangeR01AG071787 · NIA · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI MESSERSMITH, PHILLIP B, MOURRAIN, PHILIPPE · 2021 to 2025
$2.3M
Contribution of astrocytes to the Fragile X SyndromeR01MH109475 · NIMH · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI ZUO, YI · 2016 to 2020
$2.0M
BSLII Stationed Zeiss 880 Confocal Microscope with AiryscanS10OD023528 · OD · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI YILDIZ, HAVVA FITNAT · 2017 to 2017
$456k
Explore the gut-immune-brain axis mechanisms underlying perinatal penicillin exposure-induced sensory processing defectsR21HD101266 · NICHD · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI ZUO, YI · 2020 to 2021
$424k
NIA NIH HHS R01 AG071787NICHD NIH HHS R21 HD101266NIH HHS S10 OD023528NIMH NIH HHS R01 MH109475NIMH NIH HHS R01 MH127737
6 · The paper itself

Abstract

Fragile X Syndrome (FXS) is the best-known form of inherited intellectual disability caused by the loss-of-function mutation in a single gene. The

Indexed as

cell-autonomousdendritic spineFmr1FMRPFragile X syndrome (FXS)synaptic plasticity

Identifiers

PMID37035256
PMCPMC10076639
OpenAlexW4360618650

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.