ReviewCurrent oncology reports2023
Intracranial Germinomas: Diagnosis, Pathogenesis, Clinical Presentation, and Management.
Review in Current oncology reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed.
- Intracranial germ cell tumors: an underrecognized diagnostic consideration in adults with sellar/suprasellar lesions.Journal of neuro-oncology · 2026Article
- Bridging pediatric and adult neuro-oncology: Insights into adolescents and young adults (AYA) central nervous system tumors.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026Review
- Suprasellar germinoma: intraoperative findings from an endoscopic endonasal approach. Illustrative case.Journal of neurosurgery. Case lessons · 2026Article
- Unusual CNS relapse of plasma cell leukemia manifesting as multiple extra-axial brain lesions: A case report with literature review.Radiology case reports · 2026Article
- Comprehensive characterization and prognostic analysis of multifocal intracranial germ cell tumors.BMC neurology · 2026Article
- Bilateral extramidline involvement in intracranial germinoma: diagnostic lessons from a complex presentation.Arquivos de neuro-psiquiatria · 2026Article
- Article
- Beyond the tumor: endocrine and metabolic dysregulation in intracranial germ cell tumors - a retrospective cohort study.Arquivos de neuro-psiquiatria · 2025Article
- A rare presentation of pediatric germinoma mimicking optic pathway glioma: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Population pharmacokinetic model of high-dose methotrexate in Chinese patients with intracranial germ cell tumors.Frontiers in pharmacology · 2025Article
- A patient with heterochronous double primary tumor of basal ganglia germ cell tumors followed by diffuse hemispheric glioma: a case report.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Article
- Panhypopituitarism caused by a suprasellar germinoma: A case report.World journal of clinical cases · 2024Article
- A single-center experience of central nervous system tumors in children under three years old.Frontiers in pediatrics · 2024Article
- Pineal region germ cell tumors with secondary glioblastoma: A case report of long-term survival using chemoradiotherapy combined with TTFields.Neuro-oncology advancesArticle
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewIntracranial germinomas constitute a rare brain tumor entity of unknown etiology, characterized by unique histopathology and molecular biology. In this manuscript, we review the literature focusing on the epidemiology, histopathology with molecular biology, clinical presentation with emphasis on tumor location, diagnostic workup, and current treatment strategies with related clinical outcomes of intracranial germinomas. RECENT
findingsAlthough the optimal treatment strategy remains a matter of debate, intracranial germinomas respond well to radiotherapy, chemotherapy, or a combination of both and are characterized by very high cure and survival rates. It is well-known that early discrimination of germinomas from other intracranial neoplasms facilitates the timely initiation of appropriate treatment, thereby contributing to the reduction of morbidity as well as mortality. Ongoing research will need to be directed towards discovering and refining reliable parameters for early diagnosis and evaluation of prognosis in patients with intracranial germinomas.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.