Evidence mapPaperPMID 37036632Full record

ReviewCurrent urology reports2023

Imaging Techniques to Determine Degree of Sarcopenia and Systemic Inflammation in Advanced Renal Cell Carcinoma.

Benjamin N Schmeusser, Adil A Ali, Florian J Fintelmann, Jose M Garcia, Grant R Williams, Viraj A Master, Sarah P Psutka

Open access · greenAbstract readReview
In one paragraph

Review in Current urology reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Benjamin N SchmeusserDepartment of Urology, Emory University School of Medicine, 1365 Clifton Road NE, Building B, Suite 1400, Atlanta, GA, 30322, USA.ORCID http://orcid.org/0000-0002-0762-3388
Adil A AliDepartment of Urology, Emory University School of Medicine, 1365 Clifton Road NE, Building B, Suite 1400, Atlanta, GA, 30322, USA.
Florian J FintelmannDepartment of Radiology, Massachusetts General Hospital, Boston, MA, USA.
Jose M GarciaGeriatric Research, Education and Clinical Center (GRECC), VA Puget Sound Health Care System, Seattle, WA, USA.
Grant R WilliamsInstitute for Cancer Outcomes and Survivorship, University of Alabama at Birmingham, Alabama, USA.
Viraj A MasterDepartment of Urology, Emory University School of Medicine, 1365 Clifton Road NE, Building B, Suite 1400, Atlanta, GA, 30322, USA. vmaster@emory.edu.
Sarah P PsutkaDepartment of Urology, University of Washington, 1959 NE Pacific Stree, Box 356510, Seattle, WA, 98195, USA. spsutka@uw.edu.
Emory University · USMassachusetts General Hospital · USSeattle Pacific University · USUniversity of Alabama at Birmingham · USUniversity of Washington · US

Funding

Improving cancer-related fatigue, sexual dysfunction and quality of life in older men with cancer and androgen deficiencyR01AG061558 · NIA · SEATTLE INST FOR BIOMEDICAL/CLINICAL RES · 2023 to 2025
$1.3M
Improving Patient-Important Outcomes with Testosterone Replacement in Hypogonadal Men with a Prior History of CancerR01CA239208 · NCI · SEATTLE INST FOR BIOMEDICAL/CLINICAL RES · 2022 to 2025
$1.2M
BLRD VA I01 BX002807NCI NIH HHS R01 CA239208NIA NIH HHS 1R03AG073990-01A1NIA NIH HHS R01 AG061558NIA NIH HHS R03 AG073990
6 · The paper itself

Abstract

purpose of reviewThe purpose of this review is to provide an up-to-date understanding regarding the literature on sarcopenia and inflammation as prognostic factors in the context of renal cell carcinoma (RCC). RECENT

findingsSarcopenia is increasingly recognized as a prognostic factor in RCC. Emerging literature suggests monitoring quantity of muscle on successive imaging and examining muscle density may be additionally informative. Inflammation has prognostic ability in RCC and is also considered a key contributor to development and progression of both RCC and sarcopenia. Recent studies suggest these two prognostic factors together may provide additional prognostic ability when used in combination. Ongoing developments include quality control regarding sarcopenia research and imaging, improving understanding of muscle loss mechanisms, and enhancing clinical incorporation of sarcopenia via improving imaging analysis practicality (i.e., artificial intelligence) and feasible biomarkers. Sarcopenia and systemic inflammation are complementary prognostic factors for adverse outcomes in patients with RCC. Further study on high-quality sarcopenia assessment standardization and expedited sarcopenia assessment is desired for eventual routine clinical incorporation of these prognostic factors.

Indexed as

Carcinoma, Renal CellKidney NeoplasmsSarcopeniaArtificial IntelligenceHumansInflammationPrognosisRetrospective StudiesBody compositionInflammationPrognostic factorRenal cell carcinoma (RCC)SarcopeniaSkeletal muscle

Identifiers

PMID37036632
PMCPMC10330545
OpenAlexW4362735991

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.