Evidence map›Paper›PMID 37038342›Full record

ArticleAnnals of medicine2023

Efficacy of transcatheter arterial chemoembolization combined with sirolimus for treating Kasabach-Merritt phenomenon in infants, a retrospective study.

Chuan-Gao Yin, Wei-Wei Qi, Song Wang, Deng Pan, Xiao-Li Chen, Shi-Yu Li

Open access · goldAbstract read
In one paragraph

Article in Annals of medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 89% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Chuan-Gao YinDepartment of Radiology, Anhui Provincial Children's Hospital, Hefei, China.
Wei-Wei QiDepartment of Radiology, Anhui Provincial Children's Hospital, Hefei, China.
Song WangDepartment of Radiology, Anhui Provincial Children's Hospital, Hefei, China.
Deng PanDepartment of Radiology, Anhui Provincial Children's Hospital, Hefei, China.
Xiao-Li ChenDepartment of Radiology, Anhui Provincial Children's Hospital, Hefei, China.
Shi-Yu LiDepartment of Radiology, Anhui Provincial Children's Hospital, Hefei, China.
Anhui Provincial Children's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis retrospective study aimed to observe the efficacy of transcatheter arterial chemoembolization (TACE) combined with sirolimus in the treatment of haemangioma combined with the Kasabach-Merritt phenomenon (KMP).

methodsA total of 11 infants with KMP who were treated at our hospital from January 2016 to September 2021 were selected and treated with arteriosclerosis embolotherapy using a microsphere emulsion formed by bleomycin + ultra-fluid lipiodol + dexamethasone + contrast agent or bleomycin mixed microspheres as the embolising agent. The patients were administered sirolimus orally after TACE. The clinical efficacy and examination indicators before and after treatment were observed and compared.

resultsThe 11 infants underwent TACE treatment by arteriosclerosis embolotherapy a total of 21 times; of these cases, 10 were cured, and 1 showed a moderate response. There were no cases of non-response or death. The platelet count rose from 10.0 (7.0, 18.0) x 10

conclusionThe combination of TACE and sirolimus has significant efficacy on critical children with KMP.

Indexed as

Carcinoma, HepatocellularChemoembolization, TherapeuticHemangioendotheliomaKasabach-Merritt SyndromeLiver NeoplasmsSarcoma, KaposiBleomycinChildHumansInfantRetrospective StudiesSirolimusBleomycinSirolimusKaposiform haemangiomaKasabach–Merritt phenomenonsirolimusTACE

Identifiers

PMID37038342
PMCPMC10101661
OpenAlexW4363651658

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.