ArticleProceedings of the National Academy of Sciences of the United States of America2023
Pleiotropic role of TRAF7 in skull-base meningiomas and congenital heart disease.
Open access · greenAbstract read
In one paragraph
Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- European Association of Neuro-Oncology guideline on molecular testing of meningiomas for targeted therapy selection.Neuro-oncology · 2025Guideline
- Article
- Defects inFrontiers in genetics · 2026Article
- TRAF7 in signaling and disease: emerging mechanisms and clinical implications.Molecular medicine (Cambridge, Mass.) · 2025Review
- Spatial and Temporal Expression Patterns of EDA2R, PCDH9, and TRAF7 inInternational journal of molecular sciences · 2025Article
- Polycystins recruit cargo to distinct ciliary extracellular vesicle subtypes in C. elegans.Nature communications · 2025Article
- TheMicrobiology spectrum · 2024Article
- The structure of TRAF7 coiled-coil trimer provides insight into its function in zebrafish embryonic development.Journal of molecular cell biology · 2024Article
- Zebrafish Congenital Heart Disease Models: Opportunities and Challenges.International journal of molecular sciences · 2024Review
- Expression of Congenital Anomalies of the Kidney and Urinary Tract (CAKUT) Candidate GenesGenes · 2024Article
- The spectrum of heart defects in theProceedings of the National Academy of Sciences of the United States of America · 2024Article
- Reply to Pisan et al.: Pathogenicity of inherited TRAF7 mutations in congenital heart disease.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Normal meninges harbor oncogenic somatic mutations in meningioma-driver genes.Acta neuropathologica · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
30 authors at 3 institutions in 1 country.
Ketu Mishra-GorurDepartment of Neurosurgery, Yale School of Medicine, New Haven, CT 06510.ORCID 0000-0002-3182-4411
Tanyeri BarakDepartment of Neurosurgery, Yale School of Medicine, New Haven, CT 06510.
Leon D KaulenDepartment of Neurosurgery, Yale School of Medicine, New Haven, CT 06510.ORCID 0000-0002-5937-3376
Octavian HenegariuDepartment of Neurosurgery, Yale School of Medicine, New Haven, CT 06510.ORCID 0000-0002-8971-1049
Sheng Chih JinDepartment of Genetics, Yale School of Medicine, New Haven, CT 06510.
Stephanie Marie AguileraDepartment of Neurosurgery, Yale School of Medicine, New Haven, CT 06510.
Ezgi YalbirDepartment of Neurosurgery, Yale School of Medicine, New Haven, CT 06510.
Gizem GolesDepartment of Neurosurgery, Yale School of Medicine, New Haven, CT 06510.ORCID 0000-0001-7990-4878
Sayoko NishimuraDepartment of Neurosurgery, Yale School of Medicine, New Haven, CT 06510.
Danielle MiyagishimaDepartment of Neurosurgery, Yale School of Medicine, New Haven, CT 06510.
Lydia DjenouneCardiology Division, Department of Medicine, Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129.ORCID 0000-0002-9105-3575
Selin AltinokDepartment of Neurosurgery, Yale School of Medicine, New Haven, CT 06510.
Devendra K RaiDepartment of Neurosurgery, Yale School of Medicine, New Haven, CT 06510.
Stephen VivianoDepartment of Pediatrics, Yale School of Medicine, New Haven, CT 06510.ORCID 0000-0003-2059-4531
Andrew PrendergastDepartment of Internal Medicine, Section of Cardiology, Yale Cardiovascular Research Center, Yale School of Medicine, New Haven, CT 06510.
Cynthia ZerilloDepartment of Neurosurgery, Yale School of Medicine, New Haven, CT 06510.
Kent OzcanDepartment of Neurosurgery, Yale School of Medicine, New Haven, CT 06510.
Burcin BaranDepartment of Neurosurgery, Yale School of Medicine, New Haven, CT 06510.
Leman SencarDepartment of Neurosurgery, Yale School of Medicine, New Haven, CT 06510.
Nukte GocDepartment of Neurosurgery, Yale School of Medicine, New Haven, CT 06510.
Yanki YarmanDepartment of Neurosurgery, Yale School of Medicine, New Haven, CT 06510.ORCID 0000-0002-7584-6903
A Gulhan Ercan-SencicekDepartment of Neurosurgery, Yale School of Medicine, New Haven, CT 06510.
Kaya BilguvarDepartment of Genetics, Yale School of Medicine, New Haven, CT 06510.
Richard P LiftonDepartment of Genetics, Yale School of Medicine, New Haven, CT 06510.
Jennifer MoliternoDepartment of Neurosurgery, Yale School of Medicine, New Haven, CT 06510.
Angeliki LouviDepartment of Neurosurgery, Yale School of Medicine, New Haven, CT 06510.ORCID 0000-0003-1737-8707
Shiaulou YuanCardiology Division, Department of Medicine, Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129.ORCID 0000-0002-5061-6132
Engin DenizDepartment of Pediatrics, Yale School of Medicine, New Haven, CT 06510.
Martina BruecknerDepartment of Pediatrics, Yale School of Medicine, New Haven, CT 06510.ORCID 0000-0003-0347-5389
Murat GunelDepartment of Neurosurgery, Yale School of Medicine, New Haven, CT 06510.
Yale University · USHarvard University · USYale Cancer Center · US
Funding
Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9MGenetic determinants of human heterotaxy and aortic arch malformationU01HL098162 · NHLBI · YALE UNIVERSITY · PI BRUECKNER, MARTINA, GRUBER, PETER J · 2009 to 2024
$5.9MCilia in Heart Development and DiseaseR35HL145249 · NHLBI · YALE UNIVERSITY · PI BRUECKNER, MARTINA · 2019 to 2025
$5.2MOptogenetic regulation of intra-ciliary calcium signaling in cardiac situs developmentR01HL165241 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI Shiaulou Yuan · 2022 to 2026
$2.7MMolecular Mechanisms of TRAF7 Mutant Aggressive MeningiomasR01NS110824 · NINDS · YALE UNIVERSITY · PI GUNEL, MURAT · 2020 to 2024
$2.6MAnalysis of Congenital Hydrocephalus Genes in XenopusR01NS127879 · NINDS · YALE UNIVERSITY · PI ENGIN DENIZ · 2022 to 2026
$2.3MIntegrative Genomic Analysis of Congenital Heart DiseaseR00HL143036 · NHLBI · WASHINGTON UNIVERSITY · PI JIN, SHENG CHIH · 2020 to 2022
$730kXenopus as a Model System for Hydrocephaly and Ependymal CiliogenesisR21NS116484 · NINDS · YALE UNIVERSITY · PI DENIZ, ENGIN · 2020 to 2021
$433kIntegrative Genomic Analysis of Congenital Heart DiseaseK99HL143036 · NHLBI · ROCKEFELLER UNIVERSITY · PI JIN, SHENG CHIH · 2019 to 2019
$178kNCATS NIH HHS UL1 TR001863NHLBI NIH HHS K99 HL143036NHLBI NIH HHS R00 HL143036NHLBI NIH HHS R01 HL165241NHLBI NIH HHS R35 HL145249NHLBI NIH HHS U01 HL098162NINDS NIH HHS R01 NS110824NINDS NIH HHS R01 NS127879NINDS NIH HHS R21 NS116484
Abstract
While somatic variants of
Indexed as
Heart Defects, CongenitalMeningeal NeoplasmsMeningiomaAdaptor Proteins, Signal TransducingAnimalsHumansMutationSkullTumor Necrosis Factor Receptor-Associated Peptides and ProteinsZebrafishZebrafish ProteinsAdaptor Proteins, Signal TransducingIFT57 protein, zebrafishTRAF7 protein, humanTumor Necrosis Factor Receptor-Associated Peptides and ProteinsZebrafish Proteinsciliacongenital heart defectmeningiomaTRAF7
Identifiers
What Socratic holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.