Evidence map›Paper›PMID 37046091›Full record

ArticleNature2023

Chromosomal fragile site breakage by EBV-encoded EBNA1 at clustered repeats.

Julia Su Zhou Li, Ammal Abbasi, Dong Hyun Kim, Scott M Lippman, Ludmil B Alexandrov, Don W Cleveland

Open access · greenAbstract read
In one paragraph

Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
16.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 72 citations in OpenAlex.

  1. Review
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  9. Prospective Head-to-Head Comparison ofRadiology. Imaging cancer · 2026
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  12. Review
  13. The emerging role of non-Gastroenterology report · 2026
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Julia Su Zhou LiLudwig Cancer Research, UC San Diego, La Jolla, CA, USA. juliali@health.ucsd.edu.
Ammal AbbasiDepartment of Cellular and Molecular Medicine, UC San Diego, La Jolla, CA, USA.
Dong Hyun KimLudwig Cancer Research, UC San Diego, La Jolla, CA, USA.ORCID http://orcid.org/0000-0002-8762-1496
Scott M LippmanMoores Cancer Center, UC San Diego, La Jolla, CA, USA.
Ludmil B AlexandrovDepartment of Cellular and Molecular Medicine, UC San Diego, La Jolla, CA, USA.
Don W ClevelandLudwig Cancer Research, UC San Diego, La Jolla, CA, USA. dcleveland@health.ucsd.edu.ORCID http://orcid.org/0000-0002-1934-3682
University of California San Diego · USUC San Diego Health System · USPfizer (United States) · US

Funding

Mechanisms of chromosome segregation, aneuploidy, and tumorigenesisR35GM122476 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Don W Cleveland · 2017 to 2026
$9.0M
Detecting Mutational Signatures of Environmental Mutagens in Heathy Individuals for Personalized Cancer PreventionR01ES032547 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ALEXANDROV, LUDMIL B · 2021 to 2025
$3.4M
Mutational Signatures of a Combined Environmental Exposure: Arsenic and Ultraviolet RadiationR01ES030993 · NIEHS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI HUDSON, LAURIE G, LIU, KE JIAN · 2020 to 2024
$2.5M
Comprehensive identification of germline-somatic interactionsR01CA269919 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Ludmil B Alexandrov, Hannah Kathryn Carter · 2022 to 2026
$2.2M
NCI NIH HHS R01 CA269919NIEHS NIH HHS R01 ES030993NIEHS NIH HHS R01 ES032547NIGMS NIH HHS R35 GM122476
6 · The paper itself

Abstract

Epstein-Barr virus (EBV) is an oncogenic herpesvirus associated with several cancers of lymphocytic and epithelial origin

Indexed as

Chromosome BreakageDNAHerpesvirus 4, HumanViral ProteinsBinding SitesChromosomes, Human, Pair 11DNA Breaks, Double-StrandedGenomic InstabilityHumansMitosisDNAViral Proteins

Identifiers

PMID37046091
PMCPMC10328181
OpenAlexW4365143573

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.