Evidence map›Paper›PMID 37046126›Full record

ArticleCurrent microbiology2023

Transcriptional Regulation of hmsB, A Temperature-Dependent Small RNA, by RovM in Yersinia pestis Biovar Microtus.

Lei Liu, Wanbing Liu, Yingyu He, Yan Liu, Haisheng Wu, Yiquan Zhang, Qinwen Zhang

Abstract read
PubMed Publisher
In one paragraph

Article in Current microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Applied and environmental microbiology · 2024
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Lei LiuDepartment of Transfusion Medicine, General Hospital of Central Theater Command of the PLA, Wuhan, 430070, Hubei, China.
Wanbing LiuDepartment of Transfusion Medicine, General Hospital of Central Theater Command of the PLA, Wuhan, 430070, Hubei, China.
Yingyu HeDepartment of Transfusion Medicine, General Hospital of Central Theater Command of the PLA, Wuhan, 430070, Hubei, China.
Yan LiuDepartment of Transfusion Medicine, General Hospital of Central Theater Command of the PLA, Wuhan, 430070, Hubei, China.
Haisheng WuQinghai Institute for Endemic Disease Prevention and Control, Xining, 811602, China.
Yiquan ZhangQinghai Institute for Endemic Disease Prevention and Control, Xining, 811602, China. zhangyiquanq@163.com.ORCID http://orcid.org/0000-0003-3935-4079
Qinwen ZhangQinghai Institute for Endemic Disease Prevention and Control, Xining, 811602, China. 13519783993@126.com.
Central Hospital of Wuhan · CNQinghai Institute for Endemic Diease Prevention and Control · CNNantong University · CN

Funding

China Postdoctoral Science Foundation 2019M664008National Natural Science Foundation of China 81801984Zhejiang Province Public Welfare Technology Application Research Project 2020-ZJ-788
6 · The paper itself

Abstract

HmsB, a temperature-dependent sRNA, promotes biofilm formation by Yersinia pestis, but whether its own expression is regulated by other regulators is still poorly understood. RovM is a global regulator that activates biofilm formation but represses the virulence of Y. pestis. In this work, the results of primer extension, quantitative real-time PCR (qRT-PCR), and LacZ fusion demonstrated that RovM was able to activate hmsB expression. However, the results of electrophoretic mobility shift assay (EMSA) showed that His-RovM did not bind to the upstream DNA region of hmsB. Thus, RovM may exert its regulatory action on hmsB expression in an indirect manner. The data presented here enriched the content of the regulatory circuits that control gene expression in Y. pestis.

Indexed as

Yersinia pestisAnimalsArvicolinaeBacterial ProteinsGene Expression Regulation, BacterialRNATemperatureBacterial ProteinsRNA

Identifiers

PMID37046126
OpenAlexW4365443775

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.