Evidence map›Paper›PMID 37046498›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Analysis of Optical Coherence Tomography (OCT) and Optical Coherence Tomography Angiography (OCTA) Parameters in Young Adults after SARS-CoV-2 Infection (COVID-19) Compared with Healthy Young Controls.

Anahita Bajka, Daniel Rudolf Muth, Maximilian Robert Justus Wiest, Sadiq Said, Magdalena Rejdak, Sophia Sidhu, Nastasia Foa, Frank Blaser, Daniel Barthelmes, Mario Damiano Toro and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 5 countries.

Anahita Bajka *Department of Ophthalmology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland.
Daniel Rudolf Muth *Department of Ophthalmology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland.ORCID 0000-0003-3670-976X
Maximilian Robert Justus WiestDepartment of Ophthalmology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland.ORCID 0000-0002-7561-1805
Sadiq SaidDepartment of Ophthalmology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland.ORCID 0000-0003-2037-4766
Magdalena RejdakDepartment of Ophthalmology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland.ORCID 0000-0001-9156-9750
Sophia SidhuFaculty of Medicine, University of California, San Diego, CA 92093, USA.ORCID 0000-0001-5371-3483
Nastasia FoaDepartment of Ophthalmology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland.
Frank BlaserDepartment of Ophthalmology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland.
Daniel BarthelmesDepartment of Ophthalmology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland.
Mario Damiano ToroDepartment of Ophthalmology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland.
Eric H SouiedDepartment of Ophthalmology, Centre Hospitalier Intercommunal de Creteil, University Paris Est Creteil, 94000 Creteil, France.
Jeremy Werner DeuelDepartment of Global and Public Health, Epidemiology, Biostatistics and Prevention Institute, University of Zurich, 8001 Zurich, Switzerland.
Patricia SchlagenhaufDepartment of Global and Public Health, Epidemiology, Biostatistics and Prevention Institute, University of Zurich, 8001 Zurich, Switzerland.
Sandrine Anne ZweifelDepartment of Ophthalmology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland.ORCID 0000-0001-7431-1774
University of Zurich · CHMedical University of Lublin · PLUniversité Paris-Est Créteil · FRUniversity of California San Diego · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare retinal changes in young adults with previous SARS-CoV-2 infection with healthy young controls using optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA).

methodsThis prospective single-center study was conducted at the University Hospital of Zurich, Zurich, Switzerland. Participants were imaged from May to November 2021 using the

resultsIn total, 466 participants were imaged. Of these, 233 were healthy controls with negative RT-PCR tests for SARS-CoV-2, 168 were young adults who had a SARS-CoV-2 infection at least 180 days previously, 19 were participants who had a SARS-CoV-2 infection < 180 days previously, and 46 were participants with asymptomatic SARS-CoV-2 infection (i.e., serologically positive but with no symptoms). Compared with healthy controls, statistically significant differences were found for OCTA recordings of the optic disc for the whole image (WI) and WI capillary vessel density, with both being higher in the SARS-CoV-2 group.

conclusionStatistically significant results were only observed for selected variables, and in parts, only unilaterally, with relatively large

Indexed as

COVID-19LoCoMoLong-COVID in military organizationsOCTOCTAoptical coherence tomographyoptical coherence tomography angiographySARS-CoV-2

Identifiers

PMID37046498
PMCPMC10093659
OpenAlexW4361200582

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.