ArticleDiagnostics (Basel, Switzerland)2023
Comparison of Nutrition Indices for Prognostic Utility in Patients with Sepsis: A Real-World Observational Study.
Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prognostic value of nutritional assessment tools in patients with sepsis: a systematic review with meta-analysis of PNI and GNRI.Frontiers in nutrition · 2026Pooled it
- CONUT Score as a Predictor of Mortality Risk in Acute and Chronic Heart Failure: A Meta-Analytic Review.Nutrients · 2025Pooled it
- Comparison of nutritional inflammatory indicators for predicting outcomes in patients with sepsis: a retrospective study based on clinical and MIMIC data.BMC infectious diseases · 2026Article
- Prognostic Nutritional Index Predicts In-Hospital Mortality Among Patients withAntibiotics (Basel, Switzerland) · 2026Article
- Association of obesity and nutritional status on early sepsis-associated acute kidney injury in older patients with sepsis.BMC nephrology · 2026Article
- Prognostic Value of HALP and PNI Scores in Predicting 6-Month Mortality Among Geriatric Hip Fracture Patients.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- Prognostic Nutritional Index (PNI) in Patients With Diabetes and Sepsis: A Cross-Sectional Study.Cureus · 2026Article
- Association between nutritional status and sepsis-induced coagulopathy: a multicenter retrospective cohort study.Frontiers in nutrition · 2026Article
- Can Nutritional Screening Tools Predict the Prognosis of Critically Ill Patients with Sepsis?Medicina (Kaunas, Lithuania) · 2025Observational
- Investigation of the Prognostic Value of Novel Laboratory Indices in Patients with Sepsis in an Intensive Care Unit: A Retrospective Observational Study.Journal of clinical medicine · 2025Article
- The relationship between hemoglobin, albumin, lymphocyte, and platelet (HALP) score and 28-day mortality in patients with sepsis: a retrospective analysis of the MIMIC-IV database.BMC infectious diseases · 2025Article
- The V-shaped association between the ratio of neutrophil counts to prognostic nutritional index and 30-, 60-, and 90-day mortality in elderly critically ill patients aged 65 and older with sepsis: a retrospective study based on the MIMIC database.Frontiers in nutrition · 2025Article
- Association between prognostic nutritional index and all-cause mortality in critically ill patients with ventilator-associated pneumonia: a retrospective study based on MIMIC-IV database.Frontiers in nutrition · 2025Article
- Association of malnutrition status with 30-day mortality in patients with sepsis using objective nutritional indices: a multicenter retrospective study in South Korea.Acute and critical care · 2024Article
- Analysis of the predictive value of the Geriatric Nutritional Risk Index for osteoporosis in elderly patients with T2DM: a single-center retrospective study.Journal of orthopaedic surgery and research · 2023Article
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9 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundNutritional status of critically ill patients is an important factor affecting complications and mortality. This study aimed to investigate the impact of three nutritional indices, the Geriatric Nutritional Risk Index (GNRI), Prognostic Nutritional Index (PNI), and Controlling Nutritional Status (CONUT), on mortality in patients with sepsis in Japan.
methodsThis retrospective observational study used the Medical Data Vision database containing data from 42 acute-care hospitals in Japan. We extracted data on baseline characteristics on admission. GNRI, PNI, and CONUT scores on admission were also calculated. To evaluate the significance of these three nutritional indices on mortality, we used logistic regression to fit restricted cubic spline models and constructed Kaplan-Meier survival curves.
resultsWe identified 32,159 patients with sepsis according to the inclusion criteria. Of them, 1804 patients were treated in intensive care units, and 3461 patients were non-survivors. When the GNRI dropped below 100, the risk of mortality rose sharply, as did that when the PNI dropped below about 40. An increased CONUT score was associated with increased mortality in an apparent linear manner.
conclusionIn sepsis management, GNRI and PNI values may potentially be helpful in identifying patients with a high risk of death.
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