Evidence mapPaperPMID 37046607Full record

ReviewCancers2023

Experiences of Female Childhood Cancer Patients and Survivors Regarding Information and Counselling on Gonadotoxicity Risk and Fertility Preservation at Diagnosis: A Systematic Review.

Nikita H Z Clasen, M E Madeleine van der Perk, Sebastian J C M M Neggers, Annelies M E Bos, Marry M van den Heuvel-Eibrink

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
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  7. Article
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  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Nikita H Z ClasenPrincess Máxima Center for Pediatric Oncology, 3584CS Utrecht, The Netherlands.ORCID 0000-0002-4308-1854
M E Madeleine van der PerkPrincess Máxima Center for Pediatric Oncology, 3584CS Utrecht, The Netherlands.ORCID 0000-0003-0782-5307
Sebastian J C M M NeggersDepartment of Internal Medicine, Section Endocrinology, Erasmus Medical Center, 3015GD Rotterdam, The Netherlands.
Annelies M E BosPrincess Máxima Center for Pediatric Oncology, 3584CS Utrecht, The Netherlands.ORCID 0000-0003-0154-8185
Marry M van den Heuvel-EibrinkPrincess Máxima Center for Pediatric Oncology, 3584CS Utrecht, The Netherlands.ORCID 0000-0002-7760-879X
Princess Máxima Center · NLUniversity Medical Center Utrecht · NL

Funding

European Union's Horizon 2020 research and innovation programme H2020-EU.4.b 952438Princess Máxima Center Foundation Not applicableStichting Kinderoncologisch Centrum Rotterdam (sKOCR) Not applicable
6 · The paper itself

Abstract

backgroundChildhood cancer patients and their families are increasingly offered oncofertility care including information regarding their risk of gonadal damage by paediatric oncologists, fertility counselling by fertility specialists and fertility preservation options. However, experiences regarding oncofertility care are underreported. We aimed to summarize the available evidence of experiences of female childhood cancer patients and survivors regarding oncofertility care.

methodsManuscripts were systematically identified using the PubMed and Embase database. From, respectively, 1256 and 3857 manuscripts, 7 articles were included and assessed, including risk of bias assessment. Outcome measures included data describing experiences of female childhood cancer patients and survivors, regarding fertility information, counselling and/or preservation.

resultsFemale patients and survivors are variably satisfied with fertility information, report challenges in communication with healthcare professionals and prefer to receive general information at diagnosis and detailed fertility information later. Regrets after fertility counselling are underreported, but are associated with refusing fertility preservation. Lastly, regardless of counselling, female patients and survivors report fertility concerns about their future children's health and effect on relationships.

conclusionCurrently, the satisfaction with oncofertility care varies and female patients or survivors report regrets and concerns regardless of receiving fertility information or counselling. These results may help to improve the content of fertility information, communication skills of healthcare professionals and timing of counselling.

Indexed as

childhood cancercounsellingexperiencefemalegonadal damageinfertilityovarian insufficiency

Identifiers

PMID37046607
PMCPMC10093478
OpenAlexW4360862243

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.