Evidence map›Paper›PMID 37046644›Full record

ReviewCancers2023

Clinical Application of Small Extracellular Vesicles in Gynecologic Malignancy Treatments.

Fei Zheng, Jiao Wang, Dandan Wang, Qing Yang

Abstract readReview
In one paragraph

Review in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fei ZhengDepartment of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang 110004, China.
Jiao WangDepartment of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang 110004, China.
Dandan WangDepartment of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang 110004, China.
Qing YangDepartment of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang 110004, China.

Funding

Liaoning key special project of science and technology 2022JH1/10800070the 345 Talent Project (Category 30C) of the Shengjing Hospital of China Medical University No. 14 to Dandan Wangthe National Natural Science Foundation of China 82272661
6 · The paper itself

Abstract

Small extracellular vesicles (sEVs) are the key mediators of intercellular communication. They have the potential for clinical use as diagnostic or therapeutic biomarkers and have been explored as vectors for drug delivery. Identification of reliable and noninvasive biomarkers, such as sEVs, is important for early diagnosis and precise treatment of gynecologic diseases to improve patient prognosis. Previous reviews have summarized routine sEVs isolation and identification methods; however, novel and unconventional methods have not been comprehensively described. This review summarizes a convenient method of isolating sEVs from body fluids and liquid biopsy-related sEV markers for early, minimally invasive diagnosis of gynecologic diseases. In addition, the characteristics of sEVs as drug carriers and in precision treatment and drug resistance are introduced, providing a strong foundation for identifying novel and potential therapeutic targets for sEV therapy. We propose potential directions for further research on the applications of sEVs in the diagnosis and treatment of gynecologic diseases.

Indexed as

biomarkerdetectiongynecologic malignanciesisolationsmall extracellular vesiclestherapy

Identifiers

PMID37046644
PMCPMC10093031

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.